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. Author manuscript; available in PMC: 2016 Sep 10.
Published in final edited form as: Cell. 2015 Sep 10;162(6):1338–1352. doi: 10.1016/j.cell.2015.08.025

Figure 1. Melatonin levels show an inverse correlation with MS clinical relapses.

Figure 1

(a) Exacerbation rate for each season was estimated for the duration of the follow-up and depicted in the primary axis. 6-sulfatoxymelatonin levels measured in first morning urine in each season is depicted as mean ± s.e.m. in secondary axis. P value corresponds to Poisson regression model. Lack of correlation between exacerbation rate and Vitamin D (b), reported respiratory infections (c), and UV radiation in Buenos Aires city (d). See also Table 1.