Table 3.

Three-year progression-free survival rates among patients with OPC by tumor HPV DNA status or pretreatment serum HPV DNA status and smoking status

	3-year progression-free survival, % (95% CI)	P
All patients
Tumor HPV DNA status/smoking status
HPV+/≤10 pack-years	90.5 (78.6–95.9)	Reference
HPV+/>10 pack-years	78.6 (61.6–88.7)	0.887
HPV−	71.9 (47.7–86.3)	0.146 0.430a
Serum HPV DNA status/smoking status
HPV+/≤10 pack-years	86.1 (75.6–92.3)	Reference
HPV+/>10 pack-years	81.3 (66.0–90.2)	0.905
HPV−	84.9 (75.4–91.0)	0.879 0.977a
Only patients with HPV+ tumors
Serum HPV DNA status
HPV−	91.3 (75.4–97.1)	Reference
HPV+	82.1 (69.2–90.0)	0.800

^aTest for trend.