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. Author manuscript; available in PMC: 2016 Sep 15.
Published in final edited form as: Immunity. 2015 Sep 8;43(3):591–604. doi: 10.1016/j.immuni.2015.08.012

Figure 3. CD8+ T cell proliferation and apoptosis following onset of viremia.

Figure 3

(a) Representative FACS plots gated on CD8+ cells expressing Ki-67 and Bcl-2. (b) Summary data for the longitudinal analysis of proliferating and pro-apoptotic CD8+ cells for 11 donors evaluated. (c) Representative relationship between Ki67negBcl-2lowCD8+ T cells and contemporaneous viral load. (d) CD8+T cell co-expression of CD38, HLA-DR, Ki67 and Bcl-2. (e) Correlation between peak Ki67negBcl-2lowCD8+ T cells and viral load set point. Spearman’s rank correlation was used in (e).