Fig. 3.

antaRNA high-precision GC-content distribution compliance given antaRNA’s precision, it is possible for the first time to design sequences for arbitrary targeted GC-content distributions. The figure provides three examples, each comprises 100 designs for a tRNA-like structure (Supplementary Materials). The targeted distributions are drawn in gray scale [left: uniform (within interval 15–40%), middle: gaussian ($\mu =60\%,\hspace{0.17em}\sigma =6\%$)]. The 75% target value can be found on the right side. The respective achieved values are given as histograms: uniform distribution (left/1), gaussian distribution (middle/2), and single target GC value (right/3)