Fig. 2.

Changes in lipid profile and blood pressure.

Changes in the lipid profile and blood pressure were analyzed by mixed-effects model with repeated measurements (MMRM). Open and close circles represent adjusted mean, with standard error expressed by error bars. Levels of total cholesterol (A), low density lipoprotein (LDL) cholesterol (B), and triglyceride (C) were lower in the pravastatin group. Level of high density lipoprotein (HDL) cholesterol was higher in the pravastatin group (D). Systolic blood pressure (E) and diastolic blood pressure (F) were appropriately controlled in the normal ranges in both groups. Mean values (mean ± SE) of total cholesterol during follow-up periods in pravastatin group and control group were 4.75 ± 0.02 vs. 5.32 ± 0.02 mmol/L, LDL cholesterol 2.67 ± 0.02 vs. 3.22 ± 0.02 mmol/L, triglyceride 1.45 ± 0.02 vs. 1.52 ± 0.02 mmol/L, HDL cholesterol 1.44 ± 0.01 vs. 1.40 ± 0.01 mmol/L, systolic blood pressure 134.1 ± 0.38 vs. 134.4 ± 0.38 mm Hg, and diastolic blood pressure 76.8 ± 0.25 vs. 77.4 ± 0.25 mm Hg, respectively.