Skip to main content
British Heart Journal logoLink to British Heart Journal
. 1966 Jul;28(4):497–504. doi: 10.1136/hrt.28.4.497

Ions and the action of digitalis.

M Weatherall
PMCID: PMC459077  PMID: 5328943

Full text

PDF
497

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CARSLAKE M. C., WEATHERALL M. Changes in the sodium, potassium and chloride of rabbit auricles treated with ouabain. J Physiol. 1962 Sep;163:347–361. doi: 10.1113/jphysiol.1962.sp006980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. CONRAD L. L., BAXTER D. J. INTRACELLULAR DISTRIBUTION OF DIGOXIN-H3 IN THE HEARTS OF RATS AND DOGS DEMONSTRATED BY AUTORADIOGRAPHY AND ITS RELATIONSHIP TO CHANGES IN MYOCARDIAL CONTRACTILE FORCE. J Pharmacol Exp Ther. 1964 Aug;145:210–214. [PubMed] [Google Scholar]
  3. COOPERSTEIN I. L. The inhibitory effect of strophanthidin on secretion by the isolated gastric mucosa. J Gen Physiol. 1959 Jul 20;42(6):1233–1239. doi: 10.1085/jgp.42.6.1233. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Calhoun J. A., Harrison T. R. STUDIES IN CONGESTIVE HEART FAILURE: IX. The Effect of Digitalis on the Potassium Content of the Cardiac Muscle of Dogs. J Clin Invest. 1931 Apr;10(1):139–144. doi: 10.1172/JCI100334. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Clark A. J. The Influence of Ions upon the Action of Digitalis. Proc R Soc Med. 1912;5(THER):181–199. doi: 10.1177/003591571200501721. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. DUNHAM E. T., GLYNN I. M. Adenosinetriphosphatase activity and the active movements of alkali metal ions. J Physiol. 1961 Apr;156:274–293. doi: 10.1113/jphysiol.1961.sp006675. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Daly I. de B., Clark A. J. The action of ions upon the frog's heart. J Physiol. 1921 Mar 15;54(5-6):367–383. doi: 10.1113/jphysiol.1921.sp001938. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. EVANS D. H., SCHILD H. O., THESLEFF S. Effects of drugs on depolarized plain muscle. J Physiol. 1958 Oct 31;143(3):474–485. doi: 10.1113/jphysiol.1958.sp006072. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. FARBER S. J., ALEXANDER D. J., PELLEGRINO E. D., EARLE D. P. The effect of intravenously administered digoxin on water and electrolyte excretion and on renal functions. Circulation. 1951 Sep;4(3):378–386. doi: 10.1161/01.cir.4.3.378. [DOI] [PubMed] [Google Scholar]
  10. FOZZARD H. A., SMITH J. R. OBSERVATIONS ON THE LOCALIZATION OF TRITIATED DIGOXIN IN MYOCARDIAL CELLS BY AUTORADIOGRAPHY AND ULTRAMICROSCOPY: WITH ADDED REFERENCE TO THE SARCOTUBULAR SYSTEM STUDIED BY CELL FRACTIONATION AND ENZYME STAINING. Am Heart J. 1965 Feb;69:245–252. doi: 10.1016/0002-8703(65)90045-1. [DOI] [PubMed] [Google Scholar]
  11. GLYNN I. M. The action of cardiac glycosides on sodium and potassium movements in human red cells. J Physiol. 1957 Apr 3;136(1):148–173. doi: 10.1113/jphysiol.1957.sp005749. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. GOODFORD P. J., HERMANSEN K. Sodium and potassium movements in the unstriated muscle of the guinea-pig taenia coli. J Physiol. 1961 Oct;158:426–448. doi: 10.1113/jphysiol.1961.sp006778. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. HAAS H. G., GLITSCH H. G., TRAUTWEIN W. [Sodium exchange in the atrium of the frog heart]. Pflugers Arch Gesamte Physiol Menschen Tiere. 1963;277:36–47. [PubMed] [Google Scholar]
  14. HODGKIN A. L., HOROWICZ P. Movements of Na and K in single muscle fibres. J Physiol. 1959 Mar 3;145(2):405–432. doi: 10.1113/jphysiol.1959.sp006150. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. HODGKIN A. L., KEYNES R. D. Movements of labelled calcium in squid giant axons. J Physiol. 1957 Sep 30;138(2):253–281. doi: 10.1113/jphysiol.1957.sp005850. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. HUXLEY A. F., TAYLOR R. E. Local activation of striated muscle fibres. J Physiol. 1958 Dec 30;144(3):426–441. doi: 10.1113/jphysiol.1958.sp006111. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. JOHNSON J. A., SIMONDS M. A. Chemical and histological space determinations in rabbit heart. Am J Physiol. 1962 Mar;202:589–592. doi: 10.1152/ajplegacy.1962.202.3.589. [DOI] [PubMed] [Google Scholar]
  18. KAHN J. B., Jr, ACHESON G. H. Effects of cardiac glyosides and other lactones, and of certain other compounds, on cation transfer in human erythrocytes. J Pharmacol Exp Ther. 1955 Nov;115(3):305–318. [PubMed] [Google Scholar]
  19. KEYNES R. D., LEWIS P. R. The resting exchange of radioactive potassium in crab nerve. J Physiol. 1951 Mar;113(1):73–98. doi: 10.1113/jphysiol.1951.sp004557. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. KLAUS W., KUSCHINSKY G. [On the effect of digitoxigenin on the cellular calcium exchange in heart muscle tissue]. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1962;244:237–253. [PubMed] [Google Scholar]
  21. KOCH-WESER J., BLINKS J. R. THE INFLUENCE OF THE INTERVAL BETWEEN BEATS ON MYOCARDIAL CONTRACTILITY. Pharmacol Rev. 1963 Sep;15:601–652. [PubMed] [Google Scholar]
  22. LEE K. S., YU D. H., LEE D. I., BURSTEIN R. The influence of potassium and calcium on the effect of ouabain on cat papillary muscles. J Pharmacol Exp Ther. 1961 May;132:139–148. [PubMed] [Google Scholar]
  23. LULLMANN H., HOLLAND W. Influence of ouabain on an exchangeable calcium fraction, contractile force, and resting tension of guinea-pig atria. J Pharmacol Exp Ther. 1962 Aug;137:186–192. [PubMed] [Google Scholar]
  24. LUTTGAU H. C., NIEDERGERKE R. The antagonism between Ca and Na ions on the frog's heart. J Physiol. 1958 Oct 31;143(3):486–505. doi: 10.1113/jphysiol.1958.sp006073. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. MCMICHAEL J. The heart and digitalis. Br Med J. 1963 Jul 13;2(5349):73–79. doi: 10.1136/bmj.2.5349.73. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. NELSON D. A., BENSON E. S. On the structural continuities of the transverse tubular system of rabbit and human myocardial cells. J Cell Biol. 1963 Feb;16:297–313. doi: 10.1083/jcb.16.2.297. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. NIEDERGERKE R., HARRIS E. J. Accumulation of calcium (or strontium) under conditions of increasing contractility. Nature. 1957 May 25;179(4569):1068–1069. doi: 10.1038/1791068a0. [DOI] [PubMed] [Google Scholar]
  28. NIEDERGERKE R. MOVEMENTS OF CA IN FROG HEART VENTRICLES AT REST AND DURING CONTRACTURES. J Physiol. 1963 Jul;167:515–550. doi: 10.1113/jphysiol.1963.sp007166. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. NOBLE D. A modification of the Hodgkin--Huxley equations applicable to Purkinje fibre action and pace-maker potentials. J Physiol. 1962 Feb;160:317–352. doi: 10.1113/jphysiol.1962.sp006849. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. OGSTON A. G., PHELPS C. F. The partition of solutes between buffer solutions and solutions containing hyaluronic acid. Biochem J. 1961 Apr;78:827–833. doi: 10.1042/bj0780827. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. PERSOFF D. A. A comparison of methods for measuring efflux of labelled potassium from contracting rabbit atria. J Physiol. 1960 Jul;152:354–366. doi: 10.1113/jphysiol.1960.sp006492. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. RAYNER B., WEATHERALL M. Digoxin, ouabain and potassium movements in rabbit auricles. Br J Pharmacol Chemother. 1957 Sep;12(3):371–381. doi: 10.1111/j.1476-5381.1957.tb00151.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. Ringer S. A further Contribution regarding the influence of the different Constituents of the Blood on the Contraction of the Heart. J Physiol. 1883 Jan;4(1):29–42.3. doi: 10.1113/jphysiol.1883.sp000120. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. SCHATZMANN H. J. Herzglykoside als Hemmstoffe für den aktiven Kalium- und Natriumtransport durch die Erythrocytenmembran. Helv Physiol Pharmacol Acta. 1953;11(4):346–354. [PubMed] [Google Scholar]
  35. SEKUL A. A., HOLLAND W. C. Effects of ouabain on Ca45 entry in quiescent and electrically driven rabbit atria. Am J Physiol. 1960 Sep;199:457–459. doi: 10.1152/ajplegacy.1960.199.3.457. [DOI] [PubMed] [Google Scholar]
  36. Strickler J. C., Kessler R. H. DIRECT RENAL ACTION OF SOME DIGITALIS STEROIDS. J Clin Invest. 1961 Feb;40(2):311–316. doi: 10.1172/JCI104258. [DOI] [PMC free article] [PubMed] [Google Scholar]
  37. THOMAS L. J., Jr Increase of labeled calcium uptake in heart muscle during potassium lack contracture. J Gen Physiol. 1960 Jul;43:1193–1206. doi: 10.1085/jgp.43.6.1193. [DOI] [PMC free article] [PubMed] [Google Scholar]
  38. ULRICH F. Active transport of potassium by heart mitochondria. Am J Physiol. 1960 Apr;198:847–854. doi: 10.1152/ajplegacy.1960.198.4.847. [DOI] [PubMed] [Google Scholar]
  39. VAUGHAN WILLIAMS E. M. The effect of changes in extracellular potassium concentration on the intracellular potentials of isolated rabbit atria. J Physiol. 1959 Jun 11;146(3):411–428. doi: 10.1113/jphysiol.1959.sp006201. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. WALKER J. M., WEATHERALL M. CALCIUM IN RELATION TO THE ACTIONS OF OUABAIN AND ADRENALINE ON THE HEART. Br J Pharmacol Chemother. 1964 Aug;23:66–79. doi: 10.1111/j.1476-5381.1964.tb01567.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. WEATHERALL M. Quantitative analysis of movements of potassium in rabbit auricles. Proc R Soc Lond B Biol Sci. 1962 May 15;156:57–82. doi: 10.1098/rspb.1962.0028. [DOI] [PubMed] [Google Scholar]
  42. WEIDMANN S. Effect of increasing the calcium concentration during a single heart-beat. Experientia. 1959 Apr 15;15(4):128–128. doi: 10.1007/BF02165518. [DOI] [PubMed] [Google Scholar]
  43. WHITTAM R. The asymmetrical stimulation of a membrane adenosine triphosphatase in relation to active cation transport. Biochem J. 1962 Jul;84:110–118. doi: 10.1042/bj0840110. [DOI] [PMC free article] [PubMed] [Google Scholar]
  44. WINEGRAD S., SHANES A. M. Calcium flux and contractility in guinea pig atria. J Gen Physiol. 1962 Jan;45:371–394. doi: 10.1085/jgp.45.3.371. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from British Heart Journal are provided here courtesy of BMJ Publishing Group

RESOURCES