Skip to main content
NCBI home page
Thorax logoLink to Thorax
. 1982 Feb;37(2):110–113. doi: 10.1136/thx.37.2.110

Primary pulmonary histiocytosis X in two patients with Hodgkin's disease

Syed M Sajjad 1,2,3, Mario A Luna 1,2,3
PMCID: PMC459259  PMID: 6979116

Abstract

The lungs may be involved in patients with histiocytosis X as part of the generalised disease, but histiocytosis X confined to the lungs without extrapulmonary involvement is rare. This report describes two cases of primary pulmonary histiocytosis arising in patients with Hodgkin's disease. It is impossible to state with certainty whether the pulmonary histiocytosis arose as a response to the defects of cell-mediated immunity, or as a consequence of immunosuppression by radiation and chemotherapy.

Full text

PDF
110

Images in this article

111Image
on p.111
111Image
on p.111
111Image
on p.111

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AULD D. Pathology of eosinophilic granuloma of the lung. AMA Arch Pathol. 1957 Feb;63(2):113–131. [PubMed] [Google Scholar]
  2. Basset F., Nézelof C., Turiaf J. Présence en microscopie électronique de structures filamenteuses originales dans les lésions pulmonaires et osseuses de l'histiocytose x. Etat actuel de la question. Bull Mem Soc Med Hop Paris. 1966 Mar 25;117(5):413–426. [PubMed] [Google Scholar]
  3. Basset F., Soler P., Wyllie L., Mazin F., Turiaf J. Langerhans' cells and lung interstitium. Ann N Y Acad Sci. 1976;278:599–611. doi: 10.1111/j.1749-6632.1976.tb47075.x. [DOI] [PubMed] [Google Scholar]
  4. Carlson R. A., Hattery R. R., O'Connell E. J., Fontana R. S. Pulmonary involvement by histiocytosis X in the pediatric age group. Mayo Clin Proc. 1976 Sep;51(9):542–547. [PubMed] [Google Scholar]
  5. FARINACCI C. J., JEFFREY H. C., LACKEY R. W. Eosinophilic granuloma of the lung; report of two cases. U S Armed Forces Med J. 1951 Jul;2(7):1085–1093. [PubMed] [Google Scholar]
  6. Lieberman P. H., Jones C. R., Dargeon H. W., Begg C. F. A reappraisal of eosinophilic granuloma of bone, Hand-Schüller-Christian syndrome and Letterer-Siwe syndrome. Medicine (Baltimore) 1969 Sep;48(5):375–400. doi: 10.1097/00005792-196909000-00002. [DOI] [PubMed] [Google Scholar]
  7. Morgenfeld M. C., Schajowicz F. Solitary eosinophilic granuloma of lyumph node: five-year follow-up. Pediatrics. 1971 Aug;48(2):301–305. [PubMed] [Google Scholar]
  8. Nezelof C., Basset F., Rousseau M. F. Histiocytosis X histogenetic arguments for a Langerhans cell origin. Biomedicine. 1973 Sep;18(5):365–371. [PubMed] [Google Scholar]
  9. Rubé J., De la Pava S., Pickren J. W. Histiocytosis X with involvement of brain. Cancer. 1967 Apr;20(4):486–492. doi: 10.1002/1097-0142(1967)20:4<486::aid-cncr2820200405>3.0.co;2-p. [DOI] [PubMed] [Google Scholar]
  10. Silberberg-Sinakin I., Thorbecke G. J., Baer R. L., Rosenthal S. A., Berezowsky V. Antigen-bearing langerhans cells in skin, dermal lymphatics and in lymph nodes. Cell Immunol. 1976 Aug;25(2):137–151. doi: 10.1016/0008-8749(76)90105-2. [DOI] [PubMed] [Google Scholar]
  11. Stingl G., Wolff-Schreiner E. C., Pichler W. J., Gschnait F., Knapp W., Wolff K. Epidermal Langerhans cells bear Fc and C3 receptors. Nature. 1977 Jul 21;268(5617):245–246. doi: 10.1038/268245a0. [DOI] [PubMed] [Google Scholar]
  12. Tarnowski W. M., Hashimoto K. Langerhans' cell granules in histiocytosis X. The epidermal Langerhans' cell as a macrophage. Arch Dermatol. 1967 Sep;96(3):298–304. [PubMed] [Google Scholar]
  13. Vazquez J. J., Ayestaran J. R. Eosinophilic granuloma of the stomach similar to that of bone: light and electron microscopic study. Virchows Arch A Pathol Anat Histol. 1975;366(2):107–111. doi: 10.1007/BF00433584. [DOI] [PubMed] [Google Scholar]
  14. Vernon M. L., Fountain L., Krebs H. M., Horta-Barbosa L., Fuccillo D. A., Sever J. L. Birbeck granules (Langerhans' cell granules) in human lymph nodes. Am J Clin Pathol. 1973 Dec;60(6):771–779. doi: 10.1093/ajcp/60.6.771. [DOI] [PubMed] [Google Scholar]
  15. Weber W. N., Margolin F. R., Nielsen S. L. Pulmonary histiocytosis X. A review of 18 patients with reports of 6 cases. Am J Roentgenol Radium Ther Nucl Med. 1969 Oct;107(2):280–289. [PubMed] [Google Scholar]
  16. Wolff K. The langerhans cell. Curr Probl Dermatol. 1972;4:79–145. [PubMed] [Google Scholar]

Articles from Thorax are provided here courtesy of BMJ Publishing Group

RESOURCES