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. 2014 Jun 10;5(2):377–398. doi: 10.3390/insects5020377

Figure 3.

Figure 3

The HDAC inhibitor C8 impairs aversive memory but has no effect on reward memory. Bees were treated with 10 mM C8 or vehicle only, 1 h before training (A, D, G), 1 h after training (B, E, H); also shown in Figure 1, included here for comparison), or 1 h before testing (C, F, I). Panels A–C show discrimination learning and memory, panels D–F show aversive learning and memory and panels G–I show reward learning and memory, during acquisition training (A1,A2,A3) and at the retention test. 1 h before training: n C8 = 79, n vehicle = 64; 1 h after training: n C8 = 80, n vehicle = 76; 1 h before testing n C8 = 79, n vehicle = 72. * p < 0.05, ** p < 0.01, *** p < 0.001.