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. Author manuscript; available in PMC: 2016 Oct 15.
Published in final edited form as: J Immunol. 2015 Sep 4;195(8):3992–4000. doi: 10.4049/jimmunol.1501426

Figure 1.

Figure 1

Organization of kappa L chain gene clusters in the nurse shark germline. Top. Kappa gene clusters in the BAC23 clone (Ba141C21), relative position of psVκ18 deduced from another linkage relationship. The orientations and distances between clusters are unknown, the J-C intron distances are as indicated. Leader (L), VL gene segment, JL gene sement, CL exon are labeled. Bottom. Kappa split gene (left) with recombination signal sequences (RSS) shown as triangles, filled for RSS with 12 bp spacer and open for RSS with 23 bp spacer. Germline (GL)-joined (right) shown with pre-recombined VJ.