Abstract
The histories of 243 adults with cystic fibrosis were reviewed; 46 had experienced one or more spontaneous pneumothoraces (18.9%), and seven had died of this complication. There was a high incidence of recurrence on the same side after conservative management (50%) or intercostal drainage (55.2%). Prolonged intercostal drainage was associated with a high mortality. One-third of patients required surgical treatment. Twenty thoracotomies were performed. Three of these patients died but only two of the 17 survivors had recurrences. Severe airflow obstruction was not a contraindication to surgery. A plan of management for future cases is outlined.
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Selected References
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- Boat T. F., Di Sant' Agnese P. A., Warwick W. J., Handwerger S. A. Pneumothorax in cystic fibrosis. JAMA. 1969 Sep 8;209(10):1498–1504. [PubMed] [Google Scholar]
- DUNNILL M. S. Metaplastic changes in the visceral pleura in a case of fibrocystic disease of the pancreas. J Pathol Bacteriol. 1959 Jan;77(1):299–302. doi: 10.1002/path.1700770129. [DOI] [PubMed] [Google Scholar]
- Lifschitz M. I., Bowman F. O., Jr, Denning C. R., Wylie R. H. Pneumothorax as a complication of cystic fibrosis. Report of twenty cases. Am J Dis Child. 1968 Dec;116(6):633–640. doi: 10.1001/archpedi.1968.02100020637010. [DOI] [PubMed] [Google Scholar]
- Luck S. R., Raffensperger J. G., Sullivan H. J., Gibson L. E. Management of pneumothorax in children with chronic pulmonary disease. J Thorac Cardiovasc Surg. 1977 Dec;74(6):834–839. [PubMed] [Google Scholar]
- Mitchell-Heggs P. F., Batten J. C. Pleurectomy for spontaneous pneumothorax in cystic fibrosis. Thorax. 1970 Mar;25(2):165–171. doi: 10.1136/thx.25.2.165. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rich R. H., Warwick W. J., Leonard A. S. Open thoracotomy and pleural abrasion in the treatment of spontaneous pneumothorax in cystic fibrosis. J Pediatr Surg. 1978 Jun;13(3):237–242. doi: 10.1016/s0022-3468(78)80393-5. [DOI] [PubMed] [Google Scholar]
- Stowe S. M., Boat T. F., Mendelsohn H., Stern R. C., Tucker A. S., Doershuk C. F., Matthews L. W. Open thoracotomy for pneumothorax in cystic fibrosis. Am Rev Respir Dis. 1975 May;111(5):611–617. doi: 10.1164/arrd.1975.111.5.611. [DOI] [PubMed] [Google Scholar]
- Stradling P., Poole G. Conservative management of spontaneous pneumothorax. Thorax. 1966 Mar;21(2):145–149. doi: 10.1136/thx.21.2.145. [DOI] [PMC free article] [PubMed] [Google Scholar]
- di Sant'agnese P. A., Davis P. B. Cystic fibrosis in adults. 75 cases and a review of 232 cases in the literature. Am J Med. 1979 Jan;66(1):121–132. doi: 10.1016/0002-9343(79)90491-1. [DOI] [PubMed] [Google Scholar]