Article title: Somatostatin receptor subtype 4 modulates L-type calcium channels via Gγ and PKC signaling in rat retinal ganglion cells
Authors: Spring R Farrell, Donald R Rankin, Nicholas C Brecha, and Steven Barnes
Journal: Channels
Bibliometrics: Volume 8, Issue 6, Pages 519–527.
DOI: 10.4161/19336950.2014.967623
The Figures 3, 4, and 6 appeared incorrectly in print and online. The correct figures are provided below:
Figure 3.
Depolarizing pre-pulse facilitates calcium channel current but has no influence on the suppression by L-803,087. (A) Calcium channel current recorded using a pre-pulse facilitation voltage command protocol (shown below current traces) in an isolated RGC in the presence of L-803. (B) Pre-pulse facilitation was measured as the percentage increase in calcium channel current after the depolarizing step (120 mV, 50 ms). The mean facilitation in the absence (control) and presence of L-803 was the same showing that pre-pulse facilitation did not reverse the suppression of calcium channel current caused by L-803 (n = 5; 8.4 +/– 1.0 vs. 8.8 +/– 3.2% ctrl vs. L-803, paired t-test).
Figure 4.
Pre-treatment of isolated RGCs with anti-Gbg peptide reduced calcium channel suppression by L-803,087. (A) Calcium channel currents recorded from an isolated RGC pretreated with a combination of anti-Gbg peptide (1 mM) in the absence (black) and presence of L-803,087 (gray, 10 nM). (B) The mean data show that L-803,087 reduced calcium channel current in cells pre-treated with anti-Gbg peptide (n = 10, *P < 0.05, 2 way RM ANOVA).
Figure 2.
Pre-treatment of isolated RGCs with anti-Gßg peptide and GFX blocked L-803,087 induced suppression of calcium channel current. (A) Calcium channel currents recorded from an isolated RGC pre-treated with a combination of anti-Gßg peptide (1 mM) and GFX (5 mM) in the absence (black) and presence of L-803,087 (gray, 10 nM). (B) The mean data show that L-803,087 had no effect on calcium channel current in pre-treated cells (n = 6, NS 2 way RM ANOVA).