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. 1983 Apr;38(4):258–260. doi: 10.1136/thx.38.4.258

Reproducibility of histamine challenge tests in asthmatic children.

D Hariparsad, N Wilson, C Dixon, M Silverman
PMCID: PMC459530  PMID: 6867976

Abstract

The measurement of bronchial reactivity by histamine challenge testing is of increasing clinical importance in paediatrics. By means of a simple tidal breathing technique for the measurement of histamine sensitivity (expressed as PC20--the concentration of histamine which produces a 20% fall in peak flow rate) in childhood asthma, the reproducibility of pairs of tests was estimated over one hour and 24-hour intervals in 22 children. Under carefully controlled conditions the 95% confidence limits of PC20 were 0.8-1.25 X baseline PC20 after one hour and 0.36-2.8 X baseline PC20 after 24 hours.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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