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. 1983 Apr;38(4):302–306. doi: 10.1136/thx.38.4.302

Breathlessness and portable oxygen in chronic obstructive airways disease.

J C Waterhouse, P Howard
PMCID: PMC459540  PMID: 6867984

Abstract

Breathlessness was measured in 20 patients with severe chronic obstructive lung disease by the use of a visual-analogue scale. Severe resting arterial hypoxaemia was not a feature. The severity of breathlessness measured in this way did not correlate well with the results of spirometric tests or with walking ability. The use of portable oxygen was studied during simple walking tests for its effect on walking ability and the sensation of breathlessness. Portable oxygen improved exercise capacity but a placebo effect of the system probably accounted for some of the improvement. A clear improvement of distressing breathlessness was observed and represented a useful therapeutic response. Breathlessness and simple exercise ability were shown to respond independently to oxygen breathing. The value of short-term intermittent oxygen in patients with severe chronic obstructive lung disease needs to be evaluated in terms of both exercise ability and breathlessness.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Altose M. D., Shaban I. A. Intercostal muscle activity in chronic obstructive pulmonary disease. Chest. 1980 Feb;77(2 Suppl):299–300. doi: 10.1378/chest.77.2.299. [DOI] [PubMed] [Google Scholar]
  2. Bradley B. L., Garner A. E., Billiu D., Mestas J. M., Forman J. Oxygen-assisted exercise in chronic obstructive lung disease. The effect on exercise capacity and arterial blood gas tensions. Am Rev Respir Dis. 1978 Aug;118(2):239–243. doi: 10.1164/arrd.1978.118.2.239. [DOI] [PubMed] [Google Scholar]
  3. Burns B. H., Howell J. B. Disproportionately severe breathlessness in chronic bronchitis. Q J Med. 1969 Jul;38(151):277–294. [PubMed] [Google Scholar]
  4. CAMPBELL E. J., BENNETT E. D., RUBENSTEIN D. The ability to distinguish between added elastic and resistive loads to breathing. Clin Sci. 1963 Apr;24:201–207. [PubMed] [Google Scholar]
  5. CHERNIACK R. M., SNIDAL D. P. The effect of obstruction to breathing on the ventilatory response to CO2. J Clin Invest. 1956 Nov;35(11):1286–1290. doi: 10.1172/JCI103383. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. COTES J. E., GILSON J. C. Effect of oxygen on exercise ability in chronic respiratory insufficiency; use of portable apparatus. Lancet. 1956 Jun 9;270(6928):872–876. doi: 10.1016/s0140-6736(56)91341-1. [DOI] [PubMed] [Google Scholar]
  7. Guz A., Noble M. I., Widdicombe J. G., Trenchard D., Mushin W. W., Makey A. R. The role of vagal and glossopharyngeal afferent nerves in respiratory sensation, control of breathing and arterial pressure regulation in conscious man. Clin Sci. 1966 Feb;30(1):161–170. [PubMed] [Google Scholar]
  8. Guz A. Respiratory sensations in man. Br Med Bull. 1977 May;33(2):175–177. doi: 10.1093/oxfordjournals.bmb.a071419. [DOI] [PubMed] [Google Scholar]
  9. Kepron W., Cherniack R. M. The ventilatory response to hypercapnia and to hypoxemia in chronic obstructive lung disease. Am Rev Respir Dis. 1973 Oct;108(4):843–850. doi: 10.1164/arrd.1973.108.4.843. [DOI] [PubMed] [Google Scholar]
  10. Lane D. J., Howell J. B. Relationship between sensitivity to carbon dioxide and clinical features in patients with chronic airways obstruction. Thorax. 1970 Mar;25(2):150–159. doi: 10.1136/thx.25.2.150. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Liker E. S., Karnick A., Lerner L. Portable oxygen in chronic obstructive lung disease with hypoxemia and cor pulmonale. A controlled double-blind crossover study. Chest. 1975 Aug;68(2):236–241. doi: 10.1378/chest.68.2.236. [DOI] [PubMed] [Google Scholar]
  12. Matthews A. W. The relationship between central carbon dioxide sensitivity and clinical features in patients with chronic airways obstruction. Q J Med. 1977 Apr;46(182):179–195. [PubMed] [Google Scholar]
  13. McGavin C. R., Gupta S. P., McHardy G. J. Twelve-minute walking test for assessing disability in chronic bronchitis. Br Med J. 1976 Apr 3;1(6013):822–823. doi: 10.1136/bmj.1.6013.822. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Mitchell-Heggs P., Murphy K., Minty K., Guz A., Patterson S. C., Minty P. S., Rosser R. M. Diazepam in the treatment of dyspnoea in the 'Pink Puffer' syndrome. Q J Med. 1980 Winter;49(193):9–20. [PubMed] [Google Scholar]
  15. PIERCE A. K., PAEZ P. N., MILLER W. F. EXERCISE TRAINING WITH THE AID OF A PORTABLE OXYGEN SUPPLY IN PATIENTS WITH EMPHYSEMA. Am Rev Respir Dis. 1965 May;91:653–659. doi: 10.1164/arrd.1965.91.5.653. [DOI] [PubMed] [Google Scholar]
  16. Todisco T. Thoracoabdominal mechanics in dyspnea. Respiration. 1981;42(2):77–83. doi: 10.1159/000194408. [DOI] [PubMed] [Google Scholar]
  17. Woodcock A. A., Gross E. R., Geddes D. M. Oxygen relieves breathlessness in "pink puffers". Lancet. 1981 Apr 25;1(8226):907–909. doi: 10.1016/s0140-6736(81)91612-3. [DOI] [PubMed] [Google Scholar]

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