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ERK5 icKO mice do not exhibit enhanced depression after a 4 week course of CUS treatment. A, Latency to the first episode of immobility from the onset of the test, and the accumulated duration of immobility in the last 4 min of the forced-swim test. B, Latency of immobility, the total number of episodes of immobility, and the accumulated duration of immobility in the tail suspension test. n.s., Not significant.
