Abstract
The presence or absence of venous thrombosis was determined in 29 patients with an acute exacerbation of chronic obstructive lung disease by the technique of autologous platelet labelling with indium-111. Deep venous thrombosis was diagnosed in 13 patients and in nine of these patients thrombosis was located proximal to the knee--that is, in areas associated with an appreciable risk of pulmonary embolism. One patient died; pulmonary emboli were found at postmortem examination. The incidence of venous thrombosis seen in this study is high enough to suggest that these patients may benefit from prophylactic antithrombotic treatment.
Full text
PDF



Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BAUM G. L., FISHER F. D. The relationship of fatal pulmonary insufficiency with cor pulmonale, rightsided mural thrombi and pulmonary emboli: a preliminary report. Am J Med Sci. 1960 Nov;240:609–612. [PubMed] [Google Scholar]
- Belch J. J., Lowe G. D., Ward A. G., Forbes C. D., Prentice C. R. Prevention of deep vein thrombosis in medical patients by low-dose heparin. Scott Med J. 1981 Apr;26(2):115–117. doi: 10.1177/003693308102600205. [DOI] [PubMed] [Google Scholar]
- Fenech A., Hussey J. K., Smith F. W., Dendy P. P., Bennett B., Douglas A. S. Diagnosis of deep vein thrombosis using autologous indium-III-labelled platelets. Br Med J (Clin Res Ed) 1981 Mar 28;282(6269):1020–1022. doi: 10.1136/bmj.282.6269.1020. [DOI] [PMC free article] [PubMed] [Google Scholar]
- GIBBS N. M. Venous thrombosis of the lower limbs with particular reference to bed-rest. Br J Surg. 1957 Nov;45(191):209–236. doi: 10.1002/bjs.18004519102. [DOI] [PubMed] [Google Scholar]
- Moser K. M., LeMoine J. R. Is embolic risk conditioned by location of deep venous thrombosis? Ann Intern Med. 1981 Apr;94(4 Pt 1):439–444. doi: 10.7326/0003-4819-94-4-439. [DOI] [PubMed] [Google Scholar]
- Prescott S. M., Richards K. L., Tikoff G., Armstrong J. D., Jr, Shigeoka J. W. Venous thromboembolism in decompensated chronic obstructive pulmonary disease. A prospective study. Am Rev Respir Dis. 1981 Jan;123(1):32–36. doi: 10.1164/arrd.1981.123.1.32. [DOI] [PubMed] [Google Scholar]
- RYAN S. F. PULMONARY EMBOLISM AND THROMBOSIS IN CHRONIC OBSTRUCTIVE EMPHYSEMA. Am J Pathol. 1963 Nov;43:767–773. [PMC free article] [PubMed] [Google Scholar]
- Sharma G. V., Sasahara A. A. Diagnosis of pulmonary embolism in patients with chronic obstructive pulmonary disease. J Chronic Dis. 1975 Jun;28(5-6):253–257. doi: 10.1016/0021-9681(75)90008-9. [DOI] [PubMed] [Google Scholar]