Abstract
In a dose response study 12 patients with chronic bronchitis and airflow obstruction received inhaled placebo and incremental doses of oxitropium bromide. Significant improvements in peak expiratory flow rate, forced expiratory volume in one second, and forced vital capacity were recorded at all times up to 10 hours after all doses of oxitropium bromide. Oxitropium bromide is an effective bronchodilator in chronic bronchitis with an optimal dose of 400-600 micrograms.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Definition and classification of chronic bronchitis for clinical and epidemiological purposes. A report to the Medical Research Council by their Committee on the Aetiology of Chronic Bronchitis. Lancet. 1965 Apr 10;1(7389):775–779. [PubMed] [Google Scholar]
- Gregg I., Nunn A. J. Peak expiratory flow in normal subjects. Br Med J. 1973 Aug 4;3(5874):282–284. doi: 10.1136/bmj.3.5874.282. [DOI] [PMC free article] [PubMed] [Google Scholar]