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. 1985 Apr;40(4):306–311. doi: 10.1136/thx.40.4.306

Leiomyomas of the lower respiratory tract.

S H White, N B Ibrahim, C P Forrester-Wood, K Jeyasingham
PMCID: PMC460053  PMID: 4023981

Abstract

Leiomyomas account for about 2% of benign tumours of the lower respiratory tract. From the relatively few cases reported in the literature, it appears that these tumours most commonly occur in the fourth decade, although one third of patients are under the age of 20 years. The distribution of leiomyomas favours the distal part of the tracheobronchial tree and the most common site for tracheal lesions is the membranous portion of the lower third. Over 90% of pulmonary parenchymal leiomyomas, which themselves are more common in women, are incidental findings on chest radiographs whereas bronchial lesions are important causes of irreversible lung damage. Tracheal lesions may present as bronchial asthma. Accurate early diagnosis rests on a high index of clinical suspicion and histological examination of bronchoscopic biopsy specimens or frozen section material obtained at exploratory thoracotomy. Treatment could be conservative surgery, but 65% of reported cases have been managed by lobectomy or pneumonectomy as a result of advanced irreversible lung disease or unawareness of the benign nature of the lesion.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arrigoni M. G., Woolner L. B., Bernatz P. E., Miller W. E., Fontana R. S. Benign tumors of the lung. A ten-year surgical experience. J Thorac Cardiovasc Surg. 1970 Oct;60(4):589–599. [PubMed] [Google Scholar]
  2. CRASTNOPOL P., FRANKLIN W. D. Fibroleiomyoma of the lung. Ann Surg. 1957 Jan;145(1):128–132. doi: 10.1097/00000658-195701000-00016. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. FOROUGHI E. Leiomyoma of the trachea. Dis Chest. 1962 Aug;42:230–232. doi: 10.1378/chest.42.2.230. [DOI] [PubMed] [Google Scholar]
  4. GILBERT J. G., MAZZARELLA L. A., FEIT L. J. Primary tracheal tumors in the infant and adult. AMA Arch Otolaryngol. 1953 Jul;58(1):1–9. doi: 10.1001/archotol.1953.00710040018001. [DOI] [PubMed] [Google Scholar]
  5. GROVES L. K., BIDDLESTONE W. R., McCORMACK L. J. Leiomyoma of the trachea: report of a case. Cleve Clin Q. 1958 Jan;25(1):32–37. doi: 10.3949/ccjm.25.1.32. [DOI] [PubMed] [Google Scholar]
  6. Horstmann J. P., Pietra G. G., Harman J. A., Cole N. G., Grinspan S. Spontaneous regression of pulmonary leiomyomas during pregnancy. Cancer. 1977 Jan;39(1):314–321. doi: 10.1002/1097-0142(197701)39:1<314::aid-cncr2820390148>3.0.co;2-n. [DOI] [PubMed] [Google Scholar]
  7. Hurt R. Benign tumours of the bronchus and trachea, 1951-1981. Ann R Coll Surg Engl. 1984 Jan;66(1):22–26. [PMC free article] [PubMed] [Google Scholar]
  8. Jensik R. J., Faber L. P., Brown C. M., Kittle C. F. Bronchoplastic and conservative resectional procedures for bronchial adenoma. J Thorac Cardiovasc Surg. 1974 Oct;68(4):556–565. [PubMed] [Google Scholar]
  9. Kitamura S., Maeda M., Kawashima Y., Masaoka A., Manabe H. Leiomyoma of the intrathoracic trachea. Report of a case successfully treated by primary end-to-end anastomosis following circumferential resection of the trachea. J Thorac Cardiovasc Surg. 1969 Jan;57(1):126–133. [PubMed] [Google Scholar]
  10. Orlowski T. M., Stasiak K., Kolodziej J. Leiomyoma of the lung. J Thorac Cardiovasc Surg. 1978 Aug;76(2):257–261. [PubMed] [Google Scholar]
  11. PELEG H., PAUZNER Y. BENIGN TUMORS OF THE LUNG. Dis Chest. 1965 Feb;47:179–186. doi: 10.1378/chest.47.2.179. [DOI] [PubMed] [Google Scholar]
  12. SANDERS J. S., CARNES V. M. Leiomyoma of the trachea. Report of a case, with a note on the diagnosis of partial tracheal obstruction. N Engl J Med. 1961 Feb 9;264:277–279. doi: 10.1056/NEJM196102092640605. [DOI] [PubMed] [Google Scholar]
  13. Shahian D. M., McEnany M. T. Complete endobronchial excision of leiomyoma of the bronchus. J Thorac Cardiovasc Surg. 1979 Jan;77(1):87–91. [PubMed] [Google Scholar]
  14. Steiner P. E. Metastasizing fibroleiomyoma of the uterus: Report of a case and review of the literature. Am J Pathol. 1939 Jan;15(1):89–110.7. [PMC free article] [PubMed] [Google Scholar]
  15. Sweet R. S. Pulmonary leiomyoma. Am J Roentgenol Radium Ther Nucl Med. 1969 Dec;107(4):823–826. doi: 10.2214/ajr.107.4.823. [DOI] [PubMed] [Google Scholar]
  16. Taylor T. L., Miller D. R. Leiomyoma of the bronchus. J Thorac Cardiovasc Surg. 1969 Feb;57(2):284–288. [PubMed] [Google Scholar]

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