Skip to main content
NCBI home page
Thorax logoLink to Thorax
. 1986 Mar;41(3):208–209. doi: 10.1136/thx.41.3.208

Anatomical lung shunting in pulmonary fibrosis.

W C Miller, J G Heard, K M Unger, D M Suich
PMCID: PMC460295  PMID: 3715777

Abstract

Eleven patients with cryptogenic fibrosing alveolitis were evaluated for the presence of pulmonary shunting by injection of radiolabelled particles of macroaggregated albumin larger than 10 micron in diameter and by body scanning with a gamma camera. The mean shunt of 9% (SD 2%) in the patients was not significantly different from the mean shunt of 7% (2%) measured in 10 normal controls. These findings suggest that shunting is not an important part of the gas exchange abnormalities noted in such patients.

Full text

PDF
208

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Crystal R. G., Fulmer J. D., Roberts W. C., Moss M. L., Line B. R., Reynolds H. Y. Idiopathic pulmonary fibrosis. Clinical, histologic, radiographic, physiologic, scintigraphic, cytologic, and biochemical aspects. Ann Intern Med. 1976 Dec;85(6):769–788. doi: 10.7326/0003-4819-85-6-769. [DOI] [PubMed] [Google Scholar]
  2. Davis H. H., 2nd, Schwartz D. J., Lefrak S. S., Susman N., Schainker B. A. Alveolar-capillary oxygen disequilibrium in hepatic cirrhosis. Chest. 1978 Apr;73(4):507–511. doi: 10.1378/chest.73.4.507. [DOI] [PubMed] [Google Scholar]
  3. Kennedy T. C., Knudson R. J. Exercise-aggravated hypoxemia and orthodeoxia in cirrhosis. Chest. 1977 Sep;72(3):305–309. doi: 10.1378/chest.72.3.305. [DOI] [PubMed] [Google Scholar]
  4. Miller W. C., Heard J. G., Unger K. M. Enlarged pulmonary arteriovenous vessels in COPD. Another possible mechanism of hypoxemia. Chest. 1984 Nov;86(5):704–706. doi: 10.1378/chest.86.5.704. [DOI] [PubMed] [Google Scholar]
  5. Owens G. R., Rogers R. M., Pennock B. E., Levin D. The diffusing capacity as a predictor of arterial oxygen desaturation during exercise in patients with chronic obstructive pulmonary disease. N Engl J Med. 1984 May 10;310(19):1218–1221. doi: 10.1056/NEJM198405103101903. [DOI] [PubMed] [Google Scholar]
  6. Risk C., Epler G. R., Gaensler E. A. Exercise alveolar-arterial oxygen pressure difference in interstitial lung disease. Chest. 1984 Jan;85(1):69–74. doi: 10.1378/chest.85.1.69. [DOI] [PubMed] [Google Scholar]
  7. Wagner P. D., Dantzker D. R., Dueck R., de Polo J. L., Wasserman K., West J. B. Distribution of ventilation-perfusion ratios in patients with interstitial lung disease. Chest. 1976 Feb;69(2 Suppl):256–257. doi: 10.1378/chest.69.2_supplement.256-a. [DOI] [PubMed] [Google Scholar]
  8. Wolfe J. D., Tashkin D. P., Holly F. E., Brachman M. B., Genovesi M. G. Hypoxemia of cirrhosis: detection of abnormal small pulmonary vascular channels by a quantitative radionuclide method. Am J Med. 1977 Nov;63(5):746–754. doi: 10.1016/0002-9343(77)90161-9. [DOI] [PubMed] [Google Scholar]

Articles from Thorax are provided here courtesy of BMJ Publishing Group

RESOURCES