Abstract
A population based case control-study was initiated in 1981 to identify risk factors for death from asthma. Over a two year period all deaths in the Auckland population possibly due to asthma, in people less than 60 years of age, were investigated. From the 47 people who died from asthma 44 who had useful reversibility of airways obstruction (records showing greater than 20% variability of peak flow or a history indicating equivalent variability of shortness of breath) before death were selected as cases for the study. Both hospital and community based controls were used. The cases were more likely than were the community controls to have had severe disease, a hospital admission or visits to a hospital emergency department in the previous year (odds ratios 4.4, 16.0, 8.5 respectively). The asthmatic patients who died were more likely than either group of controls to have had a previous life threatening asthma attack. Poor management of the disease and poor compliance on the part of the patient increased the risk of death. In addition, use of three or more types of asthma drug within the past year was associated with an increased risk of dying that was independent of disease severity. Of interest was a similarity between asthmatic patients admitted to hospital and those who died. Nevertheless, a history of a previous life threatening attack and a recent admission to hospital identified a group at high risk.
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Selected References
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- Cochrane G. M., Clark J. H. A survey of asthma mortality in patients between ages 35 and 64 in the Greater London hospitals in 1971. Thorax. 1975 Jun;30(3):300–305. doi: 10.1136/thx.30.3.300. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fraser P. M., Speizer F. E., Waters S. D., Doll R., Mann N. M. The circumstances preceding death from asthma in young people in 1968 to 1969. Br J Dis Chest. 1971 Apr;65(2):71–84. [PubMed] [Google Scholar]
- Hetzel M. R., Clark T. J., Branthwaite M. A. Asthma: analysis of sudden deaths and ventilatory arrests in hospital. Br Med J. 1977 Mar 26;1(6064):808–811. doi: 10.1136/bmj.1.6064.808. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jackson R. T., Beaglehole R., Rea H. H., Sutherland D. C. Mortality from asthma: a new epidemic in New Zealand. Br Med J (Clin Res Ed) 1982 Sep 18;285(6344):771–774. doi: 10.1136/bmj.285.6344.771. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Johnson A. J., Nunn A. J., Somner A. R., Stableforth D. E., Stewart C. J. Circumstances of death from asthma. Br Med J (Clin Res Ed) 1984 Jun 23;288(6434):1870–1872. doi: 10.1136/bmj.288.6434.1870. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MacDonald J. B., MacDonald E. T., Seaton A., Williams D. A. Asthma deaths in Cardiff 1963-74: 53 deaths in hospital. Br Med J. 1976 Sep 25;2(6038):721–723. doi: 10.1136/bmj.2.6038.721. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Macdonald J. B., Seaton A., Williams D. A. Asthma deaths in Cardiff 1963-74: 90 deaths outside hospital. Br Med J. 1976 Jun 19;1(6024):1493–1495. doi: 10.1136/bmj.1.6024.1493. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ormerod L. P., Stableforth D. E. Asthma mortality in Birmingham 1975-7: 53 deaths. Br Med J. 1980 Mar 8;280(6215):687–690. doi: 10.1136/bmj.280.6215.687. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sutherland D. C., Beaglehole R., Fenwick J., Jackson R. T., Mullins P., Rea H. H. Death from asthma in Auckland: circumstances and validation of causes. N Z Med J. 1984 Dec 12;97(769):845–848. [PubMed] [Google Scholar]