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. 1987 Aug;42(8):573–577. doi: 10.1136/thx.42.8.573

Continuous respiratory support in quadriplegic children by bilateral phrenic nerve stimulation.

H Garrido 1, J Mazaira 1, P Gutierrez 1, E Gonzalez 1, J Rivas 1, J Madrazo 1
PMCID: PMC460854  PMID: 3499003

Abstract

Three children, aged 6-10 years, in whom cervical cord injury at the C1-C2 level resulted in apnoea had bilateral implantation of diaphragm pacemakers. With periods of gradual conditioning of the diaphragm muscle to low frequency stimulation and slow respiratory rates they adapted to continuous ventilatory support by simultaneous stimulation of both hemidiaphragms without evidence of fatigue, so far for periods of 23-47 months.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Davis J. N. Phrenic nerve conduction in man. J Neurol Neurosurg Psychiatry. 1967 Oct;30(5):420–426. doi: 10.1136/jnnp.30.5.420. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Glenn W. W., Hogan J. F., Loke J. S., Ciesielski T. E., Phelps M. L., Rowedder R. Ventilatory support by pacing of the conditioned diaphragm in quadriplegia. N Engl J Med. 1984 May 3;310(18):1150–1155. doi: 10.1056/NEJM198405033101804. [DOI] [PubMed] [Google Scholar]
  3. Glenn W. W., Hogan J. F., Phelps M. L. Ventilatory support of the quadriplegic patient with respiratory paralysis by diaphragm pacing. Surg Clin North Am. 1980 Oct;60(5):1055–1078. doi: 10.1016/s0039-6109(16)42233-4. [DOI] [PubMed] [Google Scholar]
  4. Glenn W. W., Holcomb W. G., McLaughlin A. J., O'Hare J. M., Hogan J. F., Yasuda R. Total ventilatory support in a quadriplegic patient with radiofrequency electrophrenic respiration. N Engl J Med. 1972 Mar 9;286(10):513–516. doi: 10.1056/NEJM197203092861004. [DOI] [PubMed] [Google Scholar]
  5. Glenn W. W. Pacing the diaphragm in infants. Ann Thorac Surg. 1985 Oct;40(4):319–320. doi: 10.1016/s0003-4975(10)60059-8. [DOI] [PubMed] [Google Scholar]
  6. Hunt C. E., Matalon S. V., Thompson T. R., Demuth S., Loew J. M., Liu H. M., Mastri A., Burke B. Central hypoventilation syndrome: experience with bilateral phrenic nerve pacing in 3 neonates. Am Rev Respir Dis. 1978 Jul;118(1):23–28. doi: 10.1164/arrd.1978.118.1.23. [DOI] [PubMed] [Google Scholar]
  7. Ilbawi M. N., Idriss F. S., Hunt C. E., Brouillette R. T., DeLeon S. Y. Diaphragmatic pacing in infants: techniques and results. Ann Thorac Surg. 1985 Oct;40(4):323–329. doi: 10.1016/s0003-4975(10)60061-6. [DOI] [PubMed] [Google Scholar]
  8. Kim J. H., Manuelidis E. E., Glen W. W., Kaneyuki T. Diaphragm pacing: histopathological changes in the phrenic nerve following long-term electrical stimulation. J Thorac Cardiovasc Surg. 1976 Oct;72(4):602–608. [PubMed] [Google Scholar]
  9. Oda T., Glenn W. W., Fukuda Y., Hogan J. F., Gorfien J. Evaluation of electrical parameters for diaphragm pacing: an experimental study. J Surg Res. 1981 Feb;30(2):142–153. doi: 10.1016/0022-4804(81)90006-8. [DOI] [PubMed] [Google Scholar]
  10. Radecki L. L., Tomatis L. A. Continuous bilateral electrophrenic pacing in an infant with total diaphragmatic paralysis. J Pediatr. 1976 Jun;88(6):969–971. doi: 10.1016/s0022-3476(76)81051-7. [DOI] [PubMed] [Google Scholar]
  11. Shaw R. K., Glenn W. W., Hogan J. F., Phelps M. L. Electrophysiological evaluation of phrenic nerve function in candidates for diaphragm pacing. J Neurosurg. 1980 Sep;53(3):345–354. doi: 10.3171/jns.1980.53.3.0345. [DOI] [PubMed] [Google Scholar]

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