Abstract
Breathing patterns early and late in the night, at the same sleep stage, were compared in six healthy subjects and 15 adults with nocturnal asthma, to try to identify changes of overnight bronchoconstriction, and breathing patterns at different sleep stages, to see whether there were changes related to sleep stages that were indicative of bronchoconstriction. Despite an average 31% fall in FEV1 overnight in the patients with asthma, neither breathing frequency nor expiratory time, which might be expected to change during bronchoconstriction, was different early in the night from late in the night, nor did they differ between sleep stages. There was no evidence of asynchronous movement of the chest and abdomen in any patient. This study did not identify any abnormality of breathing pattern that would indicate the development of nocturnal asthma without the need to awaken the patient.
Full text
PDF



Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Catterall J. R., Douglas N. J., Calverley P. M., Brash H. M., Brezinova V., Shapiro C. M., Flenley D. C. Irregular breathing and hypoxaemia during sleep in chronic stable asthma. Lancet. 1982 Feb 6;1(8267):301–304. doi: 10.1016/s0140-6736(82)91567-7. [DOI] [PubMed] [Google Scholar]
- Catterall J. R., Rhind G. B., Stewart I. C., Whyte K. F., Shapiro C. M., Douglas N. J. Effect of sleep deprivation on overnight bronchoconstriction in nocturnal asthma. Thorax. 1986 Sep;41(9):676–680. doi: 10.1136/thx.41.9.676. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Chadha T. S., Schneider A. W., Birch S., Jenouri G., Sackner M. A. Breathing pattern during induced bronchoconstriction. J Appl Physiol Respir Environ Exerc Physiol. 1984 Apr;56(4):1053–1059. doi: 10.1152/jappl.1984.56.4.1053. [DOI] [PubMed] [Google Scholar]
- Douglas N. J., Brash H. M., Wraith P. K., Calverley P. M., Leggett R. J., McElderry L., Flenley D. C. Accuracy sensitivity to carboxyhemoglobin, and speed of response of the Hewlett-Packard 47201A ear oximeter. Am Rev Respir Dis. 1979 Feb;119(2):311–313. doi: 10.1164/arrd.1979.119.2.311. [DOI] [PubMed] [Google Scholar]
- Douglas N. J., Calverley P. M., Leggett R. J., Brash H. M., Flenley D. C., Brezinova V. Transient hypoxaemia during sleep in chronic bronchitis and emphysema. Lancet. 1979 Jan 6;1(8106):1–4. doi: 10.1016/s0140-6736(79)90451-3. [DOI] [PubMed] [Google Scholar]
- Hetzel M. R., Clark T. J. Does sleep cause nocturnal asthma? Thorax. 1979 Dec;34(6):749–754. doi: 10.1136/thx.34.6.749. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hillman D. R., Prentice L., Finucane K. E. The pattern of breathing in acute severe asthma. Am Rev Respir Dis. 1986 Apr;133(4):587–592. doi: 10.1164/arrd.1986.133.4.587. [DOI] [PubMed] [Google Scholar]
- Issa F. G., Sullivan C. E. Respiratory muscle activity and thoracoabdominal motion during acute episodes of asthma during sleep. Am Rev Respir Dis. 1985 Nov;132(5):999–1004. doi: 10.1164/arrd.1985.132.5.999. [DOI] [PubMed] [Google Scholar]
- Kelsen S. G., Prestel T. F., Cherniack N. S., Chester E. H., Deal E. C., Jr Comparison of the respiratory responses to external resistive loading and bronchoconstriction. J Clin Invest. 1981 Jun;67(6):1761–1768. doi: 10.1172/JCI110215. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mann J., Bradley C. A., Anthonisen N. R. Occlusion pressure in acute bronchospasm induced by methylcholine. Respir Physiol. 1978 Jun;33(3):339–347. doi: 10.1016/0034-5687(78)90060-9. [DOI] [PubMed] [Google Scholar]
- Pardy R. L., Rivington R. N., Milic-Emili J., Mortola J. P. Control of breathing in chronic obstructive pulmonary disease. The effect of histamine inhalation. Am Rev Respir Dis. 1982 Jan;125(1):6–11. doi: 10.1164/arrd.1982.125.1.6. [DOI] [PubMed] [Google Scholar]
- Shapiro C. M., Catterall J. R., Montgomery I., Raab G. M., Douglas N. J. Do asthmatics suffer bronchoconstriction during rapid eye movement sleep? Br Med J (Clin Res Ed) 1986 May 3;292(6529):1161–1164. doi: 10.1136/bmj.292.6529.1161. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Smith T. F., Hudgel D. W. Arterial oxygen desaturation during sleep in children with asthma and its relation to airway obstruction and ventilatory drive. Pediatrics. 1980 Nov;66(5):746–751. [PubMed] [Google Scholar]
- Tabachnik E., Muller N. L., Levison H., Bryan A. C. Chest wall mechanics and pattern of breathing during sleep in asthmatic adolescents. Am Rev Respir Dis. 1981 Sep;124(3):269–273. doi: 10.1164/arrd.1981.124.3.269. [DOI] [PubMed] [Google Scholar]
- Tobin M. J., Birch S., Jenouri G., Sackner M. A. Acute effects of aerosolized metaproterenol on breathing pattern of patients with symptomatic bronchial asthma. J Allergy Clin Immunol. 1985 Aug;76(2 Pt 1):166–172. doi: 10.1016/0091-6749(85)90696-7. [DOI] [PubMed] [Google Scholar]
