Table 3.

Associations between the Oxidative Balance Score and lipids/lipoproteins in the REGARDS cohort

Biomarker	LS mean (SD)	Normal biomarker levels (n)	Abnormal biomarker levels (n)	OR (95% CI)d	p- trende
Elevated serum total cholesterola
OBS Interval
3–7	194 (39)	482	376	1.0	0.05
8–12	192 (41)	3,622	2,422	0.89 (0.77 – 1.03)
13–17	190 (43)	5,359	3,485	0.85 (0.74 – 0.99)
18–21	190 (41)	2,232	1,442	0.84 (0.72 – 0.99)
22–26	189 (38)	223	147	0.85 (0.66 – 1.10)
Elevated serum LDL-cholesterolb
OBS Interval
3–7	116 (34)	263	585	1.0	<0.01
8–12	114 (36)	2,113	3,817	0.85 (0.73 – 0.99)
13–17	113 (38)	3,204	5,465	0.80 (0.69 – 0.93)
18–21	113 (36)	1,387	2,218	0.75 (0.64 – 0.89)
22–26	112 (34)	141	223	0.75 (0.58 – 0.98)
Elevated serum triglyceridesc
OBS Interval
3–7	130 (88)	613	345	1.0	0.17
8–12	129 (87)	4,229	1,811	1.05 (0.89 – 1.23)
13–17	129 (92)	6,344	2,496	0.98 (0.83 – 1.15)
18–21	128 (90)	2,630	1,044	0.99 (0.83 – 1.18)
22–26	132 (83)	255	115	1.11 (0.84 – 1.47)

^aCholesterol cutoffs: normal cholesterol, <200 mg/dL (n=11,918); High cholesterol, ≥200 mg/dL (n=7,872)

^bLDL cutoffs: normal LDL, <100mg/dL (n=7,108); high LDL, ≥100 mg/dL (n=12,308)

^cTriglycerides cutoffs: normal triglycerides, < 150 mg/dL (n=14,071); high triglycerides, ≥150 mg/dL (n=5,711)

^dAdjusted for age, sex, race, BMI, total daily energy, education, region, and exercise

^eX² test