Table 1.
Antigen | Adjuvant | Chlamydia muridarum-specific ELISA antibody titre | Serum neutralizing titre | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Serum | Vaginal wash | ||||||||||
IgM | IgG | IgG1 | IgG2a | IgG2b | IgG3 | IgA | IgG | IgA | |||
MOMP | CpG+Montanide | 100 | 51 200 | 6400 | 51 200 | 51 200 | 6400 | 1600 | 320 | 20 | 6250 |
Ovalbumin | CpG+Montanide | <100 | <100 | <100 | <100 | <100 | <100 | <100 | <10 | <10 | <50 |
MOMP | CpG+Alum | <100 | 1600 | 800 | 1600 | 1600 | 800 | 200 | 20 | 10 | 250 |
Ovalbumin | CpG+Alum | <100 | <100 | <100 | <100 | <100 | <100 | <100 | <10 | <10 | <50 |
Cm EB | <100 | 12 800 | 1600 | 12 800 | 12 800 | 3200 | 1600 | 40 | 160 | 1250 | |
MEM | <100 | <100 | <100 | <100 | <100 | <100 | <100 | <10 | <10 | <50 |
EB, elementary body; MEM, minimal essential medium; MOMP, major outer membrane protein.