Abstract
Research with sodium iso-nonanoyl oxybenzene sulphonate (SINOS) for use in a detergent product was complicated by the development of asthma in an atopic 38 year old laboratory technician. Inhalation challenge tests with nebulised SINOS solutions over a dose range of 0.01-32 micrograms gave reproducible late asthmatic reactions after the higher doses and an increase in bronchial responsiveness to methacholine. The magnitude of the late reaction was related to the challenge dose.
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Selected References
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- Burge P. S., Perks W. H., O'Brien I. M., Burge A., Hawkins R., Brown D., Green M. Occupational asthma in an electronics factory: a case control study to evaluate aetiological factors. Thorax. 1979 Jun;34(3):300–307. doi: 10.1136/thx.34.3.300. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hendrick D. J., Fabbri L. M., Hughes J. M., Banks D. E., Barkman H. W., Jr, Connolly M. J., Jones R. N., Weill H. Modification of the methacholine inhalation test and its epidemiologic use in polyurethane workers. Am Rev Respir Dis. 1986 Apr;133(4):600–604. doi: 10.1164/arrd.1986.133.4.600. [DOI] [PubMed] [Google Scholar]
- Lam S., Chan-Yeung M. Ethylenediamine-induced asthma. Am Rev Respir Dis. 1980 Jan;121(1):151–155. doi: 10.1164/arrd.1980.121.1.151. [DOI] [PubMed] [Google Scholar]
- Lozewicz S., Davison A. G., Hopkirk A., Burge P. S., Boldy D. A., Riordan J. F., McGivern D. V., Platts B. W., Davies D., Newman Taylor A. J. Occupational asthma due to methyl methacrylate and cyanoacrylates. Thorax. 1985 Nov;40(11):836–839. doi: 10.1136/thx.40.11.836. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pepys J., Pickering C. A., Breslin A. B., Terry D. J. Asthma due to inhaled chemical agents, tolylene di-isocyanate. Clin Allergy. 1972 Sep;2(3):225–236. doi: 10.1111/j.1365-2222.1972.tb01287.x. [DOI] [PubMed] [Google Scholar]