. 2015 Oct 20;3:e1290. doi: 10.7717/peerj.1290

Table 1. Quality parameters in the elderly resuscitation bundle.

1	Lactate: Measured before or within 1 h after blood culture.
2	Blood culture: Drawn before antibiotics.
3	Antibiotic: Administered within 1 h of severe sepsis onset.
4	Fluid: Fluid given until one of the following
	a. CVP ≥ 8 (on MV 12) mmHg.
	b. MAP ≥ 65 mmHg and lactate < 2.5 mmol/L and UO > 0.5 mL/kgh.
	c. 12 L of crystalloid equivalent.
5	Vasopressor: Administered for 1 of the following
	a. MAP < 65 mmHg despite fluid challenge.
	b. MAP < 50 mmHg for ≥ 15 min.
6	RBC: Transfused if Hct < 30% and ScVO₂ < 70% or mixed venous O2 sat < 65% despite fluid resuscitation (RBC before adequate fluid resuscitation is inappropriate).
7	Inotrope: Started if Hct ≥ 30% and ScVO₂ < 70% or mixed venous O2 sat < 65% despite fluid resuscitation (inotrope before adequate fluid resuscitation is inappropriate).

Notes.