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. 1989 Apr;44(4):307–309. doi: 10.1136/thx.44.4.307

Sulfadoxine specific lymphocyte transformation in a patient with eosinophilic pneumonia induced by sulfadoxine-pyrimethamine (Fansidar).

P T Daniel 1, J Holzschuh 1, P A Berg 1
PMCID: PMC461805  PMID: 2763233

Abstract

A patient developed eosinophilic peripheral pulmonary infiltrates while receiving malaria prophylaxis with sulfadoxine-pyrimethamine (Fansidar). Withdrawal of Fansidar and treatment with corticosteroids led to rapid recovery. No exacerbation occurred after cessation of corticosteroids. Lymphocyte transformation testing gave a positive result in the presence of sulfadoxine but not pyrimethamine. It is concluded that drug hypersensitivity to sulfadoxine was the cause of the eosinophilic pneumonia in this patient.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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