Article title: “Interferon regulatory factor 1 and histone H4 acetylation in systemic lupus erythematosus”
Authors: Yiu Tak Leung, Lihua Shi, Kelly Maurer, Li Song, Zhe Zhang, Michelle Petri, and Kathleen E Sullivan
Journal: Epigenetics
Bibliometrics: Volume 10, Issue 3, pages 191–199
DOI: 10.1080/15592294.2015.1009764
An incorrect version of Figure 6 was published in the original online and print publications. The correct version of Figure 6 is published below:
Figure 6.
IRF1 interactions with HATs and HDACs. (A) An IRF1 co-immunoprecipitation survey of HATs active on H4 lysine groups is shown. IRF1 interactions were examined under unstimulated conditions, as well as a time course of IFN-a stimulation over 24 h. IRF1 binds with PCAF and ATF2 in both unstimulated and stimulated states. IRF1 interactions induced by IFN-a stimulation are seen with CBP, p300, GCN5. Mouse IgG was used as a negative control for the immunoprecipitation. The positive control for each individual HAT is shown in the lysate column. (B) An IRF1 co-immunoprecipitation survey with selected HDACs is shown. IRF1 association with HDAC3 is seen at 1 h after IFN-a stimulation and disassociates by 4 h. (C) The IRF1 immunoprecipitation for the HAT study is shown to demonstrate that IRF1 recovery was comparable across all time points.
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