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. 2014 Dec 6;9(11):1521–1531. doi: 10.4161/15592294.2014.983371

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© 2014 Taylor & Francis Group, LLC

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Figure 1. — Patterns of Histone H3K9 Acetylation in Early Regenerating Liver. Examples of gene-specific patterns of histone acetylation in regenerating vs. sham-operated liver are shown for several specific genes identified as (A) hyperacetylated (Ccnd1, Myc, Ahr, Cdkn1a) or (B) deacetylated (Cebpa, Foxo3, Nr3c1, Gas1) 12 hours after PH. UCSC gene maps (transcription (*) and translation (**) start sites, exons (E), and introns (I) as designated) are aligned with abundance of immunoprecipitated sequence (sequence reads per bp with scale indicated to the right) integrated from livers of 3 replicates each after PH or sham surgery. The sequence abundance images were generated using the Integrative Genomics Viewer (IGV) genome browser.^40,41 The bars below the sequence abundance data indicate specific sequence(s) identified as differentially acetylated.