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. 2014 Dec 6;9(11):1521–1531. doi: 10.4161/15592294.2014.983371

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Figure 4. — Hepatic mRNA Expression of Differentially Acetylated Genes during and Model of Epigenetic Regulation of Liver Regeneration. (A) Relative mRNA expression (± standard error) 12 hours after PH or sham surgery (indexed to sham; *P < 0 .05 for PH vs. sham; n = 6 replicates per experimental group) or 12 hours after PH in vehicle- (Veh) or SAHA-treated mice (indexed to Veh; *P < 0 .05 for SAHA vs. vehicle; n = 6 replicates per experimental group). (B) Proposed model of epigenetically regulated Myc/Foxo3 switch in regenerating liver (known positive (→) and negative (—|) regulation and hypothesized (?) regulation as indicated; see text for additional discussion).