Table 1.

Summary of differentially acetylated genes in liver 12 hr after PH vs. Sham Surgery (FDR<0.1)

	Total (unique)	GO terms enriched for differentially acetylated genes	Number of genes linked to3:
Effect of PH	genes1	(FDR<0.1)2	Cell proliferation4	Cell Death4
Decreased Acetylation	454 (392)	cellular ketone metabolic process, regulation of cell death, lipid metabolic process, regulation of programmed cell death, sulfur amino acid metabolic process, organic acid metabolic process	37	31
Increased Acetylation	480 (410)	gland development, cellular process, system development, anatomical structure development, organ development, multicellular organismal development, lactation, developmental process, cellular metabolic process, regulation of cell cycle, vasculature development	36	8

¹In PH vs. Sham replicates.

²Identified using DAVID bioinformatics database (see references 11–12) from GOTERM_BP_ALL, PANTHER_BP_ALL, KEGG_PATHWAY, PANTHER_PATHWAY on significantly de- or hyper-acetylated genes, respectively.

³Based on examination of all terms into which DAVID sorted differentially acetylated genes.

⁴See Table 2 for specific genes.