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. 1990 May;45(5):416–418. doi: 10.1136/thx.45.5.416

Choriocarcinoma with lung metastases during pregnancy with successful delivery and outcome after chemotherapy.

J Nabers 1, T A Splinter 1, H C Wallenburg 1, F J ten Kate 1, R Oosterom 1, C Hilvering 1
PMCID: PMC462498  PMID: 2382249

Abstract

A patient with an intrauterine pregnancy of 27 weeks had a coexisting pulmonary metastatic choriocarcinoma. On the chest radiograph the lung metastases appeared as pulmonary infiltrates, simulating atypical pneumonia. Serum human chorionic gonadotrophin levels were normal for gestational age. Treatment with methotrexate was successful. This is the first reported case of choriocarcinoma in a woman with a pregnancy of less than 35 weeks in which both mother and child survived. The case emphasises the need to consider choriocarcinoma in any pregnant woman who presents with haemoptysis and pulmonary nodules or infiltrates.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BAGSHAWE K. D., GARNETT E. S. RADIOLOGICAL CHANGES IN THE LUNGS OF PATIENTS WITH TROPHOBLASTIC TUMOURS. Br J Radiol. 1963 Sep;36:673–679. doi: 10.1259/0007-1285-36-429-673. [DOI] [PubMed] [Google Scholar]
  2. Brewer J. I., Mazur M. T. Gestational choriocarcinoma. Its origin in the placenta during seemingly normal pregnancy. Am J Surg Pathol. 1981 Apr;5(3):267–277. doi: 10.1097/00000478-198104000-00007. [DOI] [PubMed] [Google Scholar]
  3. Eriksson A., Gezelius C. Metastatic choriocarcinoma during normal pregnancy presenting as thyroid tumor. Arch Gynecol. 1984;236(2):119–122. doi: 10.1007/BF02134008. [DOI] [PubMed] [Google Scholar]
  4. Kuhn R. J., Long A. R., Fortune D. W. Choriocarcinoma coexistent with intrauterine pregnancy. Aust N Z J Obstet Gynaecol. 1980 May;20(2):94–98. doi: 10.1111/j.1479-828x.1980.tb00102.x. [DOI] [PubMed] [Google Scholar]
  5. Libshitz H. I., Baber C. E., Hammond C. B. The pulmonary metastases of choriocarcinoma. Obstet Gynecol. 1977 Apr;49(4):412–416. [PubMed] [Google Scholar]
  6. McCue S. A., Greene J. B. Metastatic cerebral choriocarcinoma during pregnancy. Minn Med. 1980 Mar;63(3):164–166. [PubMed] [Google Scholar]
  7. McLeod D. T. Gestational choriocarcinoma presenting as endobronchial carcinoma. Thorax. 1988 May;43(5):410–411. doi: 10.1136/thx.43.5.410. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Pushchak M. J., Farhi D. C. Primary choriocarcinoma of the lung. Arch Pathol Lab Med. 1987 May;111(5):477–479. [PubMed] [Google Scholar]
  9. van der Werf A. J., Broeders G. H., Vooys G. P., Mastboom J. L. Metastatic choriocarcinoma as a complication of pregnancy. Obstet Gynecol. 1970 Jan;35(1):78–88. [PubMed] [Google Scholar]

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