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. 1990 Aug;45(8):597–601. doi: 10.1136/thx.45.8.597

Assessment of the right ventricle by magnetic resonance imaging in chronic obstructive lung disease.

L W Turnbull 1, J P Ridgway 1, W Biernacki 1, H McRitchie 1, A L Muir 1, J J Best 1, W MacNee 1
PMCID: PMC462637  PMID: 2402721

Abstract

Right ventricular wall and chamber volume were measured by magnetic resonance imaging in 16 patients with stable chronic obstructive lung disease who subsequently underwent measurement of pulmonary haemodynamics by right heart catheterisation. The patients had a forced expiratory volume in one second of 0.7 (SD 0.3) litres, a forced vital capacity of 2.4 (1.0) l, an arterial oxygen tension (PaO2) of 6.5 (1.3) kPa, an arterial carbon dioxide tension (PaCO2) of 6.5 (1.0) kPa, and a mean pulmonary arterial pressure 30 (10) mm Hg. The mean right ventricular free wall volume was 57.1 (22.6) cm3, compared with a mean value of 115.0 (44.3) cm3 for the left ventricle and interventricular septal volume. The right ventricular chamber volume at end systole was 44.8 (23.4) cm3, whereas the left ventricular end systolic chamber volume was 51.1 (35.1) cm3. The right ventricular free wall volume correlated with the right ventricular chamber volume (r = 0.71), systolic (r = 0.74) and mean (r = 0.72) pulmonary arterial pressure, pulmonary vascular resistance (r = 0.67), and PaCO2 (r = 0.56). There was no significant correlation between the right ventricular free wall volume and PaO2 or the right ventricular ejection fraction, measured by radionuclide ventriculography. Assessment of the right ventricle by magnetic resonance imaging may help to better define patients with cor pulmonable and assess the long term effects of treatment in such patients.

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Selected References

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  1. ABER G. M., BAYLEY T. J., BISHOP J. M. INTER-RELATIONSHIPS BETWEEN RENAL AND CARDIAC FUNCTION AND RESPIRATORY GAS EXCHANGE IN OBSTRUCTIVE AIRWAYS DISEASE. Clin Sci. 1963 Oct;25:159–170. [PubMed] [Google Scholar]
  2. Arcilla R. A., Tsai P., Thilenius O., Ranniger K. Angiographic method for volume estimation of right and left ventricles. Chest. 1971 Nov;60(5):446–454. doi: 10.1378/chest.60.5.446. [DOI] [PubMed] [Google Scholar]
  3. Astorri E., Chizzola A., Visioli O., Anversa P., Olivetti G., Vitali-Mazza L. Right ventricular hypertrophy--a cytometric study on 55 human hearts. J Mol Cell Cardiol. 1971 Jun;2(2):99–110. doi: 10.1016/0022-2828(71)90064-2. [DOI] [PubMed] [Google Scholar]
  4. Biernacki W., Flenley D. C., Muir A. L., MacNee W. Pulmonary hypertension and right ventricular function in patients with COPD. Chest. 1988 Dec;94(6):1169–1175. doi: 10.1378/chest.94.6.1169. [DOI] [PubMed] [Google Scholar]
  5. FULTON R. M., HUTCHINSON E. C., JONES A. M. Ventricular weight in cardiac hypertrophy. Br Heart J. 1952 Jul;14(3):413–420. doi: 10.1136/hrt.14.3.413. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Foale R., Nihoyannopoulos P., McKenna W., Kleinebenne A., Nadazdin A., Rowland E., Smith G., Klienebenne A. Echocardiographic measurement of the normal adult right ventricle. Br Heart J. 1986 Jul;56(1):33–44. doi: 10.1136/hrt.56.1.33. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Foraker A. G., Bedrossian C. W., Anderson A. E., Jr Myocardial dimensions and proportions in pulmonary emphysema. Arch Pathol. 1970 Oct;90(4):344–347. [PubMed] [Google Scholar]
  8. France A. J., Prescott R. J., Biernacki W., Muir A. L., MacNee W. Does right ventricular function predict survival in patients with chronic obstructive lung disease? Thorax. 1988 Aug;43(8):621–626. doi: 10.1136/thx.43.8.621. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Gentzler R. D., 2nd, Briselli M. F., Gault J. H. Angiographic estimation of right ventricular volume in man. Circulation. 1974 Aug;50(2):324–330. doi: 10.1161/01.cir.50.2.324. [DOI] [PubMed] [Google Scholar]
  10. Howard P. Drugs or oxygen for hypoxic cor pulmonale? Br Med J (Clin Res Ed) 1983 Oct 22;287(6400):1159–1160. doi: 10.1136/bmj.287.6400.1159. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Leach E., Howard P., Barer G. R. Resolution of hypoxic changes in the heart and pulmonary arterioles of rats during intermittent correction of hypoxia. Clin Sci Mol Med. 1977 Feb;52(2):153–162. doi: 10.1042/cs0520153. [DOI] [PubMed] [Google Scholar]
  12. Longmore D. B., Klipstein R. H., Underwood S. R., Firmin D. N., Hounsfield G. N., Watanabe M., Bland C., Fox K., Poole-Wilson P. A., Rees R. S. Dimensional accuracy of magnetic resonance in studies of the heart. Lancet. 1985 Jun 15;1(8442):1360–1362. doi: 10.1016/s0140-6736(85)91786-6. [DOI] [PubMed] [Google Scholar]
  13. MICHELSON N. Bilateral ventricular hypertrophy due to chronic pulmonary disease. Dis Chest. 1960 Oct;38:435–446. doi: 10.1378/chest.38.4.435. [DOI] [PubMed] [Google Scholar]
  14. MacNee W., Wathen C. G., Flenley D. C., Muir A. D. The effects of controlled oxygen therapy on ventricular function in patients with stable and decompensated cor pulmonale. Am Rev Respir Dis. 1988 Jun;137(6):1289–1295. doi: 10.1164/ajrccm/137.6.1289. [DOI] [PubMed] [Google Scholar]
  15. MacNee W., Xue Q. F., Hannan W. J., Flenley D. C., Adie C. J., Muir A. L. Assessment by radionuclide angiography of right and left ventricular function in chronic bronchitis and emphysema. Thorax. 1983 Jul;38(7):494–500. doi: 10.1136/thx.38.7.494. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Matsukubo H., Matsuura T., Endo N., Asayama J., Watanabe T. Echocardiographic measurement of right ventricular wall thickness. A new application of subxiphoid echocardiography. Circulation. 1977 Aug;56(2):278–284. doi: 10.1161/01.cir.56.2.278. [DOI] [PubMed] [Google Scholar]
  17. Murphy M. L., Adamson J., Hutcheson F. Left ventricular hypertrophy in patients with chronic bronchitis and emphysema. Ann Intern Med. 1974 Sep;81(3):307–313. doi: 10.7326/0003-4819-81-3-307. [DOI] [PubMed] [Google Scholar]
  18. Padmavati S., Raizada V. Electrocardiogram in chronic cor pulmonale. Br Heart J. 1972 Jul;34(7):658–667. doi: 10.1136/hrt.34.7.658. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Prakash R. Determination of right ventricular wall thickness in systole and diastole. Echocardiographic and necropsy correlation in 32 patients. Br Heart J. 1978 Nov;40(11):1257–1261. doi: 10.1136/hrt.40.11.1257. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. REINER L., MAZZOLENI A., RODRIGUEZ F. L., FREUDENTHAL R. R. The weight of the human heart. I. Normal cases. AMA Arch Pathol. 1959 Jul;68(1):58–73. [PubMed] [Google Scholar]
  21. Smith M. A., Ridgway J. P., Brydon J. W., Been M., Douglas R. H., Kean D. M., Muir A. L., Best J. J. ECG-gated T1 images of the heart. Phys Med Biol. 1986 Jul;31(7):771–778. doi: 10.1088/0031-9155/31/7/007. [DOI] [PubMed] [Google Scholar]
  22. Suzuki J., Sakamoto T., Takenaka K., Kawakubo K., Amano K., Takahashi H., Hasegawa I., Shiota T., Hada Y., Sugimoto T. Assessment of the thickness of the right ventricular free wall by magnetic resonance imaging in patients with hypertrophic cardiomyopathy. Br Heart J. 1988 Nov;60(5):440–445. doi: 10.1136/hrt.60.5.440. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Timms R. M., Khaja F. U., Williams G. W. Hemodynamic response to oxygen therapy in chronic obstructive pulmonary disease. Ann Intern Med. 1985 Jan;102(1):29–36. doi: 10.7326/0003-4819-102-1-29. [DOI] [PubMed] [Google Scholar]
  24. Weitzenblum E., Moyses B., Dickele M. C., Methlin G. Detection of right ventricular pressure overloading by thallium-201 myocardial scintigraphy. Results in 57 patients with chronic respiratory diseases. Chest. 1984 Feb;85(2):164–169. doi: 10.1378/chest.85.2.164. [DOI] [PubMed] [Google Scholar]
  25. Weitzenblum E., Zielinski J., Bishop J. M. The diagnosis of "cor pulmonale" by non-invasive methods: a challenge for pulmonologists and cardiologists. Bull Eur Physiopathol Respir. 1983 Sep-Oct;19(5):423–426. [PubMed] [Google Scholar]

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