Table 4.
Multivariate models for quality of life (QOL) measures in overweight/obese breast cancer survivors (N = 692)a
| QOL Physical R2=0.47 | QOL Mental R2=0.33 | IOC Positive Impact Scale R2=0.14 | IOC Negative Impact Scale R2=0.40 | |||||
|---|---|---|---|---|---|---|---|---|
| β Coefficient | P Value | β Coefficient | P Value | β Coefficient | P Value | β Coefficient | P Value | |
| Age | - | - | - | - | - | - | −.012 | <.0001 |
| Race/ethnicity | ||||||||
| African-American | - | - | - | - | .225 | .002 | −.366 | <.0001 |
| Asian | - | - | - | - | .542 | .001 | - | - |
| Hispanic | - | - | - | - | .203 | .02 | - | - |
| Education | - | - | −.045 | .05 | −.159 | .0002 | - | - |
| Not married | - | - | −.098 | .0003 | - | - | - | - |
| Time since diagnosis | .001 | .04 | - | - | - | - | - | - |
| Cancer stage | - | - | - | - | - | - | .257 | .0007 |
| Chemotherapy | - | - | - | - | .233 | <.0001 | - | - |
| Hospitalizations in last year | −.052 | .001 | - | - | - | - | - | - |
| Emergency room visits in last year | −.088 | .001 | - | - | - | - | - | - |
| No. of prescription medications | −.022 | .001 | - | - | - | - | .032 | .05 |
| Moderate/vigorous activity | .011 | .01 | .013 | .01 | - | - | - | - |
| CES-D Score* | −.008 | <.0001 | x | x | −.013 | .0005 | .031 | <.0001 |
| BCPT symptom clusters** | ||||||||
| Nausea | −.075 | .003 | −.073 | .02 | - | - | - | - |
| Bladder control | - | - | −.032 | .03 | - | - | - | - |
| Musculoskeletal pain | −.115 | <.001 | - | - | - | - | - | |
| Cognitive problems | - | - | −.127 | <.0001 | .081 | .004 | .069 | .02 |
| Weight problems | - | - | −.041 | .0007 | - | - | .115 | <.0001 |
| Arm problems | −.035 | .01 | - | - | - | - | .082 | .01 |
a
Values shown are β coefficients and P values for significant associations with each of the four outcomes, when controlled for all variables tabulated. A dash (-) indicates nonsignificant terms in the models. Quality of life outcomes were log transformed. No significant associations were identified for BMI, number of co-morbidities, or endocrine therapy with any of the QOL outcomes.
*
CES-D score was omitted as a predictor for QOL Mental because of high correlation between the two (rho = −0.72).
**
BCPT symptom clusters for hot flashes and vaginal problems were not associated with any QOL indicators.