Table 3.
The comparison of sensitivity and specificity of threshold values of diagnostic tools for prediabetes, DM and glucose intolerance diagnosis
| Diagnostic tool | Optimal threshold valuea | Sensitivity | Specificity | |
|---|---|---|---|---|
| Prediabetesb | FPG (mg/dl) | 96.50 | 0.721 | 0.868 |
| Glycated hemoglobin (%) | 5.60 | 0.706 | 0.816 | |
| Fructosamine (µmol/l) | 230.50 | 0.676 | 0.579 | |
| 1,5-AG (nmol/ml) | 38.79 | 0.618 | 0.711 | |
| HOMA-IR | 3.00 | 0.618 | 0.684 | |
| DM | FPG (mg/dl) | 112.50 | 0.727 | 0.953 |
| Glycated hemoglobin (%) | 5.99 | 0.864 | 0.726 | |
| Fructosamine (µmol/l) | 249.50 | 0.727 | 0.755 | |
| 1,5-AG (nmol/ml) | 30.97 | 0.591 | 0.443 | |
| HOMA-IR | 3.21 | 0.818 | 0.585 | |
| Glucose intolerance | FPG (mg/dl) | 97.50 | 0.744 | 0.947 |
| Glycated hemoglobin (%) | 5.60 | 0.767 | 0.816 | |
| Fructosamine (µmol/l) | 233.50 | 0.656 | 0.632 | |
| 1,5-AG (nmol/ml) | 33.22 | 0.633 | 0.658 | |
| HOMA-IR | 3.00 | 0.678 | 0.684 |
Total study population (128 patients) was analyzed for the evaluation of the markers as a diagnostic tool for DM and glucose intolerance
aThreshold value for each diagnostic tool calculated as the nearest point of ROC curve that sensitivity 100 %, false positivity is 0 %
bDM patients were excluded (106 patients were analyzed) for the evaluation of the markers as a diagnostic tool for Prediabetes