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. 2015 Nov 3;10(11):e0141645. doi: 10.1371/journal.pone.0141645

Correction: Distribution and Frequency of kdr Mutations within Anopheles gambiae s.l. Populations and First Report of the Ace.1G119S Mutation in Anopheles arabiensis from Burkina Faso (West Africa)

Roch K Dabiré, Moussa Namountougou, Abdoulaye Diabaté, Dieudonné D Soma, Joseph Bado, Hyacinthe K Toé, Chris Bass, Patrice Combary
PMCID: PMC4631493  PMID: 26528719

There is an error in the fifth sentence of the Abstract. The correct sentence is: Furthermore we report, for the first time, the identification of the ace.1 G119S mutation in An. arabiensis populations collected at 8 sites.

There is also an error in the first sentence of the Discussion section. The correct sentence is: This study provides current information on the distribution of three members of the Anopheles gambiae complex across Burkina Faso and the frequency and distribution of three important target-site resistance mechanisms in these populations.

In Tables 2 and 3, the values in the column [95% CI] are incorrect. Please view the corrected Tables 2 and 3 here.

Table 2. Allelic and genotypic frequencies at the kdr 1014F and 1014S locus in An. gambiae s.l populations.

Species Sites N Genotypes Genotypes
1014L 1014L 1014F f(L1014F) [95%Cl] p(HW) 1014L 1014L f(L1014F) [95%Cl] p(HW)
1014L 1014F 1014F 1014L 1014F
An. arabiensis Gaoua 5 1 0 2 0.66 [0.24–1] - 0 2 0.66 [0.24–1] 0.2000
Banfora 0 0 0 0 - - - 0 0 0 - -
Sindou 10 5 0 0 0 - - 1 4 0.9 [0.71–1] -
Orodara 1 1 0 0 0 - 0.4678 0 0 0 - -
Dioulassoba 30 1 5 14 0.82 [0.68–0.95] 0.2308 2 8 0.42 [0.24–0.59] 0.0003
Soumousso 11 1 1 5 0.78 [0.53–1] 0.0956 2 2 0.37 [0.08–0.65] 0.2914
Boromo 17 2 3 12 0.79 [0.59–0.98] 0.000 6 3 0.28 [0.06–0.49] 0.3405
Dédougou 23 6 0 10 0.62 [0.42–0.81] 0.1652 5 2 0 - 0.3213
Koudougou 13 2 3 8 0.73 [0.48–0.97] - 0 0 0.5 [0.22–0.77] -
Nanoro 6 4 0 0 0 - 0.4406 0 2 0.5 [0.09–0.90] 0.0857
Koupela 13 2 3 3 0.56 [0.29–0.82] 0.2970 2 3 0.53 [0.25–0.80] 0.1795
Fada 25 6 5 3 0.39 [0.19–0.58] 0.0933 8 3 0.57 [0.37–0.76] 0.9035
Kaya 17 4 3 5 0.54 [0.30–0.77] - 1 4 0.37 [0.14–0.59] 0.0061
Ouahigouya 1 0 1 0 0.5 [0–1] 0.0031 0 0 0 - -
Dori 22 6 2 8 0.56 0.35–0.76] - 4 2 0.26 [0.07–0.44] 0.2260
An. coluzzii Gaoua 1 1 0 0 0 - - 0 0 0 - -
Banfora 7 0 1 5 0.91 [6.69–1] - 0 1 0.16 [0–0.43] 0.0909
Sindou 12 1 1 4 0.75 [0.50–0.99] 0.2727 1 5 0.91 [0.74–1 -
Orodara 5 2 1 1 0.37 [0–0.79] 0.4286 1 0 0.12 [0–0.40] -
Dioulassoba 9 1 1 3 0.7 [0.40–0.99] 0.3333 1 3 0.7 [0.40–0.99] 0.3333
Soumousso 4 2 1 0 0.16 [0–0.51] - 0 1 0.33 [0–0.79] 0.2000
Boromo 0 0 0 0 - - - 0 0 - - -
Dédougou 3 1 1 0 0.25 [0–0.74] - 0 1 0.5 [0–1] 0.6190
Koudougou 7 0 3 2 0.7 |0.36–1] 1 2 0 0.2 [0–0.5] -
Nanoro 39 1 5 18 0.85 [0.73–0.96] 0.3983 12 3 0.37 [0.21–0.52] 0.3333
Koupela 9 3 5 0 0.31 |0–0.61] 1 1 0 0.06 [0–0.21] 0.7446
Fada 46 7 7 13 0.61 [0.46–0.75] 0.0186 17 2 0.38 [0.23–0.52] 0.0817
Kaya 8 2 0 3 0.6 [0.26–0.93] 0.0476 2 1 0.4 [0.06–0.73] 0.3333
Ouahigouya 17 4 0 6 0.6 [0.36–0.83 0.0017 2 5 0.6 [0.36–0.83] 1
Dori 9 3 0 2 0.4 [0.07–0.72] 0.0476 1 3 0.7 [0.40–0.99] -
An. gambiae Gaoua 74 14 8 17 0.53 [0.41–0.64] 0.0002 0 35 0.92 [0.85–0.98] 1
Banfora 29 7 7 10 0.56 [0.37–0.74] 0.0434 3 2 0.14 [0.01–0.26] 0.1518
Sindou 46 8 3 13 0.6 [0.45–0.74] 0.0003 5 17 0.81 [0.69–0.92] 0.0611
Orodara 33 5 7 11 0.63 [0.46–0.79] 0.0904 1 9 0.41 [0.24–0.57] 0.0420
Dioulassoba 8 0 1 3 0.87 [0.63–1] - 2 2 0.75 [0.44–1] 0.3257
Soumousso 29 8 9 3 0.37 [0.19–0.54] 0.5690 5 4 0.32 [0.15–0.48] 0.0000
Boromo 25 8 7 1 0.28 |0.10–0.45] 0.7912 4 5 0.43 [0.23–0.62] 0.1201
Dédougou 19 5 0 7 0.58 [0.35–0.80] 0.0004 7 0 0.29 [0.08–0.49] 0.0150
Koudougou 26 9 2 8 0.47 [0.27–0.66] 0.0005 4 3 0.26 [0.09–0.42] 1
Nanoro 5 1 0 3 0.75 [0.37–1] 0.1429 0 1 0.25 [0–0.62] 0.1429
Koupela 24 7 1 6 0.46 [0.26–0.65] 0.0013 4 6 0.57 [0.37–0.76] 0.0003
Fada 30 3 9 7 0.6 [0.42–0.77] 0.6254 5 6 0.44 [0.26–0.61] 0.0473
Kaya 19 5 7 3 0.43 [0.20–0.65] 0.5785 3 1 0.16 [0–0.32] 0.0000
Ouahigouya 30 10 3 7 0.42 [0.24–0.59] 0.0020 2 8 0.45 [0.27–0.62] 0.0632
Dori 18 4 4 4 0.5 [0.26–0.73] 0.2300 1 5 0.55 [0.32–0.77] 0.0520

N: number of mosquitoes

f(1014F): frequency of the kdr W resistant allele

f(1014S): frequency of the kdr E resistant allele

p(HW): probability of the exact test for goodness of fit to Hardy Weinberg equilibrium

-: not determined

Table 3. Allelic and genotypic frequencies at the ace-1 locus in An. gambiae s.l populations from 15 sites in Burkina Faso.

Species Sites N Genotypes f(119S) [95%Cl] p(HW)
119G 119G 119G 119S 119S 119S
An. arabiensis Gaoua 3 3 0 0 0 - -
Banfora 0 0 0 0 - - -
Sindou 5 5 5 0 0 - -
Orodara 1 1 1 0 0 - -
Dioulassoba 20 4 4 12 0.7 [0.49–0.90] 0.0264
Soumousso 7 1 1 5 0.78 [0.47–1] 0.2308
Boromo 15 5 9 1 0.36 [0.11–0.60] 0.9488
Dédougou 14 4 6 4 0.5 [0.23–0.76] 0.0444
Koudougou 12 5 0 7 0.58 [0.30–0.85] 0.0004
Nanoro 3 2 0 1 0.33 [0–0.86] 0.2000
Koupela 8 8 0 0 0 - -
Fada 13 4 8 1 0.38 [0.11–0.64] 0.9449
Kaya 12 11 0 1 0.08 [0–0.23] 0.0435
Ouahigouya 1 1 0 0 0 - -
Dori 14 14 0 0 0 - -
An. coluzzii Gaoua 1 1 0 0 0 - -
Banfora 6 6 0 0 0 - -
Sindou 6 6 0 0 0 - -
Orodara 4 4 0 0 0 - -
Dioulassoba 5 4 1 0 0.1 [0–0.36] -
Soumousso 3 3 0 0 0 - -
Boromo 0 0 0 0 - - -
Dédougou 2 0 0 2 0.5 [0–1] 1
Koudougou 5 2 3 0 0.3 [0–0.70] 1
Nanoro 23 17 6 0 0.13 [0–0.26] 1
Koupela 8 6 2 0 0.12 [0–0.34] 1
Fada 27 27 0 0 0 - -
Kaya 5 5 0 0 0 - -
Ouahigouya 9 6 3 0 0.16 [0–0.39] 1
Dori 5 5 0 0 0 - -
An. gambiae Gaoua 36 22 11 3 0.23 [0.09–0.36] 0.2811
Banfora 24 20 4 0 0.08 [0–0.18] 1
Sindou 24 21 3 0 0.06 [0–0.15] 1
Orodara 23 22 0 1 0.04 [0–0.12] 0.0222
Dioulassoba 4 4 0 0 0 - -
Soumousso 20 18 0 2 0.1 [0–0.23] 0.0021
Boromo 15 9 4 2 0.26 [0.03–0.48] 0.2260
Dédougou 12 8 4 0 0.16 [0–0.36] 1
Koudougou 18 14 1 3 0.19 [0–0.37] 0.0029-
Nanoro 4 3 1 0 0.12 [0–0.43] -
Koupela 12 12 0 0 0 - -
Fada 19 18 0 1 0.05 [0–14] 0.0270
Kaya 15 11 4 0 0.13 [0–0.30] 1
Ouahigouya 19 14 2 3 0.21 [0.02–0.39] 0.0096
Dori 11 10 0 1 0.09 [0–0.25] 0.0476

N: number of mosquitoes

f(119S): frequency of the 119S resistant ace.1 allele

p(HW): probability of the exact test for goodness of fit to Hardy Weinberg equilibrium

-: not determined

Reference

  • 1. Dabiré RK, Namountougou M, Diabaté A, Soma DD, Bado J, Toé HK, et al. (2014) Distribution and Frequency of kdr Mutations within Anopheles gambiae s.l. Populations and First Report of the Ace.1G119S Mutation in Anopheles arabiensis from Burkina Faso (West Africa). PLoS ONE 9(7): e101484 doi:10.1371/journal.pone.0101484 [DOI] [PMC free article] [PubMed] [Google Scholar]

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