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. 1992 Feb;47(2):70–75. doi: 10.1136/thx.47.2.70

Randomised controlled trial of weightlifting exercise in patients with chronic airflow limitation.

K Simpson 1, K Killian 1, N McCartney 1, D G Stubbing 1, N L Jones 1
PMCID: PMC463573  PMID: 1549826

Abstract

BACKGROUND PATIENTS: with chronic airflow obstruction are often limited by muscle fatigue and weakness. As exercise rehabilitation programmes have produced modest improvements at best a study was designed to determine whether specific muscle training techniques are helpful. METHODS: Thirty four patients with chronic airflow limitation (forced expiratory volume in one second (FEV1) 38% of predicted values) were stratified for FEV1 to vital capacity (VC) ratio less than 40% and arterial oxygen desaturation during exercise and randomised to a control or weightlifting training group. In the experimental group training was prescribed for upper and lower limb muscles as a percentage of the maximum weight that could be lifted once only. It was carried out three times a week for eight weeks. RESULTS: Three subjects dropped out of each group; results in the remaining 14 patients in each group were analysed. Adherence in the training group was 90%. In the trained subjects muscle strength and endurance time during cycling at 80% of maximum power output increased by 73% from 518 (SE69) to 898 (95) s, with control subjects showing no change (506 (86) s before training and 479 (89) s after training). No significant changes in maximum cycle ergometer exercise capacity or distance walked in six minutes were found in either group. Responses to a chronic respiratory questionnaire showed significant improvements in dyspnoea and mastery of daily living activities in the trained group. CONCLUSIONS: Weightlifting training may be successfully used in patients with chronic airflow limitation, with benefits in muscle strength, exercise endurance, and subjective responses to some of the demands of daily living.

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Selected References

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  1. Alpert J. S., Bass H., Szucs M. M., Banas J. S., Dalen J. E., Dexter L. Effects of physical training on hemodynamics and pulmonary function at rest and during exercise in patients with chronic obstructive pulmonary disease. Chest. 1974 Dec;66(6):647–651. doi: 10.1378/chest.66.6.647. [DOI] [PubMed] [Google Scholar]
  2. BLAKEMORE W. S., FORSTER R. E., MORTON J. W., OGILVIE C. M. A standardized breath holding technique for the clinical measurement of the diffusing capacity of the lung for carbon monoxide. J Clin Invest. 1957 Jan;36(1 Pt 1):1–17. doi: 10.1172/JCI103402. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bass H., Whitcomb J. F., Forman R. Exercise training: therapy for patients with chronic obstructive pulmonary disease. Chest. 1970 Feb;57(2):116–121. doi: 10.1378/chest.57.2.116. [DOI] [PubMed] [Google Scholar]
  4. Belman M. J., Kendregan B. A. Exercise training fails to increase skeletal muscle enzymes in patients with chronic obstructive pulmonary disease. Am Rev Respir Dis. 1981 Mar;123(3):256–261. doi: 10.1164/arrd.1981.123.3.256. [DOI] [PubMed] [Google Scholar]
  5. Black L. F., Hyatt R. E. Maximal respiratory pressures: normal values and relationship to age and sex. Am Rev Respir Dis. 1969 May;99(5):696–702. doi: 10.1164/arrd.1969.99.5.696. [DOI] [PubMed] [Google Scholar]
  6. Borg G. A. Psychophysical bases of perceived exertion. Med Sci Sports Exerc. 1982;14(5):377–381. [PubMed] [Google Scholar]
  7. Brown A. B., McCartney N., Sale D. G. Positive adaptations to weight-lifting training in the elderly. J Appl Physiol (1985) 1990 Nov;69(5):1725–1733. doi: 10.1152/jappl.1990.69.5.1725. [DOI] [PubMed] [Google Scholar]
  8. Butland R. J., Pang J., Gross E. R., Woodcock A. A., Geddes D. M. Two-, six-, and 12-minute walking tests in respiratory disease. Br Med J (Clin Res Ed) 1982 May 29;284(6329):1607–1608. doi: 10.1136/bmj.284.6329.1607. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Chester E. H., Belman M. J., Bahler R. C., Baum G. L., Schey G., Buch P. Multidisciplinary treatment of chronic pulmonary insufficiency. 3. The effect of physical training on cardiopulmonary performance in patients with chronic obstructive pulmonary disease. Chest. 1977 Dec;72(6):695–702. doi: 10.1378/chest.72.6.695. [DOI] [PubMed] [Google Scholar]
  10. Crapo R. O., Morris A. H., Clayton P. D., Nixon C. R. Lung volumes in healthy nonsmoking adults. Bull Eur Physiopathol Respir. 1982 May-Jun;18(3):419–425. [PubMed] [Google Scholar]
  11. Crapo R. O., Morris A. H., Gardner R. M. Reference spirometric values using techniques and equipment that meet ATS recommendations. Am Rev Respir Dis. 1981 Jun;123(6):659–664. doi: 10.1164/arrd.1981.123.6.659. [DOI] [PubMed] [Google Scholar]
  12. Crapo R. O., Morris A. H. Standardized single breath normal values for carbon monoxide diffusing capacity. Am Rev Respir Dis. 1981 Feb;123(2):185–189. doi: 10.1164/arrd.1981.123.2.185. [DOI] [PubMed] [Google Scholar]
  13. Degre S., Sergysels R., Messin R., Vandermoten P., Salhadin P., Denolin H., De Coster A. Hemodynamic responses to physical training in patients with chronic lung disease. Am Rev Respir Dis. 1974 Oct;110(4):395–402. doi: 10.1164/arrd.1974.110.4.395. [DOI] [PubMed] [Google Scholar]
  14. Frontera W. R., Meredith C. N., O'Reilly K. P., Knuttgen H. G., Evans W. J. Strength conditioning in older men: skeletal muscle hypertrophy and improved function. J Appl Physiol (1985) 1988 Mar;64(3):1038–1044. doi: 10.1152/jappl.1988.64.3.1038. [DOI] [PubMed] [Google Scholar]
  15. Guyatt G. H., Berman L. B., Townsend M., Pugsley S. O., Chambers L. W. A measure of quality of life for clinical trials in chronic lung disease. Thorax. 1987 Oct;42(10):773–778. doi: 10.1136/thx.42.10.773. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Guyatt G. H., Sullivan M. J., Thompson P. J., Fallen E. L., Pugsley S. O., Taylor D. W., Berman L. B. The 6-minute walk: a new measure of exercise capacity in patients with chronic heart failure. Can Med Assoc J. 1985 Apr 15;132(8):919–923. [PMC free article] [PubMed] [Google Scholar]
  17. Guyatt G. H., Thompson P. J., Berman L. B., Sullivan M. J., Townsend M., Jones N. L., Pugsley S. O. How should we measure function in patients with chronic heart and lung disease? J Chronic Dis. 1985;38(6):517–524. doi: 10.1016/0021-9681(85)90035-9. [DOI] [PubMed] [Google Scholar]
  18. Jaeschke R., Singer J., Guyatt G. H. Measurement of health status. Ascertaining the minimal clinically important difference. Control Clin Trials. 1989 Dec;10(4):407–415. doi: 10.1016/0197-2456(89)90005-6. [DOI] [PubMed] [Google Scholar]
  19. Jones N. L. Evaluation of a microprocessor-controlled exercise testing system. J Appl Physiol Respir Environ Exerc Physiol. 1984 Nov;57(5):1312–1318. doi: 10.1152/jappl.1984.57.5.1312. [DOI] [PubMed] [Google Scholar]
  20. Jones N. L., Jones G., Edwards R. H. Exercise tolerance in chronic airway obstruction. Am Rev Respir Dis. 1971 Apr;103(4):477–491. doi: 10.1164/arrd.1971.103.4.477. [DOI] [PubMed] [Google Scholar]
  21. Jones N. L., Summers E., Killian K. J. Influence of age and stature on exercise capacity during incremental cycle ergometry in men and women. Am Rev Respir Dis. 1989 Nov;140(5):1373–1380. doi: 10.1164/ajrccm/140.5.1373. [DOI] [PubMed] [Google Scholar]
  22. Levine S., Weiser P., Gillen J. Evaluation of a ventilatory muscle endurance training program in the rehabilitation of patients with chronic obstructive pulmonary disease. Am Rev Respir Dis. 1986 Mar;133(3):400–406. doi: 10.1164/arrd.1986.133.3.400. [DOI] [PubMed] [Google Scholar]
  23. Marsh E., Sale D., McComas A. J., Quinlan J. Influence of joint position on ankle dorsiflexion in humans. J Appl Physiol Respir Environ Exerc Physiol. 1981 Jul;51(1):160–167. doi: 10.1152/jappl.1981.51.1.160. [DOI] [PubMed] [Google Scholar]
  24. McCartney N., McKelvie R. S., Haslam D. R., Jones N. L. Usefulness of weightlifting training in improving strength and maximal power output in coronary artery disease. Am J Cardiol. 1991 May 1;67(11):939–945. doi: 10.1016/0002-9149(91)90164-g. [DOI] [PubMed] [Google Scholar]
  25. McCartney N., Moroz D., Garner S. H., McComas A. J. The effects of strength training in patients with selected neuromuscular disorders. Med Sci Sports Exerc. 1988 Aug;20(4):362–368. doi: 10.1249/00005768-198808000-00006. [DOI] [PubMed] [Google Scholar]
  26. McGavin C. R., Gupta S. P., Lloyd E. L., McHardy G. J. Physical rehabilitation for the chronic bronchitic: results of a controlled trial of exercises in the home. Thorax. 1977 Jun;32(3):307–311. doi: 10.1136/thx.32.3.307. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. McGavin C. R., Gupta S. P., McHardy G. J. Twelve-minute walking test for assessing disability in chronic bronchitis. Br Med J. 1976 Apr 3;1(6013):822–823. doi: 10.1136/bmj.1.6013.822. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Mertens D. J., Shephard R. J., Kavanagh T. Long-term exercise therapy for chronic obstructive lung disease. Respiration. 1978;35(2):96–107. doi: 10.1159/000193865. [DOI] [PubMed] [Google Scholar]
  29. Moritani T., deVries H. A. Potential for gross muscle hypertrophy in older men. J Gerontol. 1980 Sep;35(5):672–682. doi: 10.1093/geronj/35.5.672. [DOI] [PubMed] [Google Scholar]
  30. Paez P. N., Phillipson E. A., Masangkay M., Sproule B. J. The physiologic basis of training patients with emphysema. Am Rev Respir Dis. 1967 Jun;95(6):944–953. doi: 10.1164/arrd.1967.95.6.944. [DOI] [PubMed] [Google Scholar]
  31. Ries A. L., Ellis B., Hawkins R. W. Upper extremity exercise training in chronic obstructive pulmonary disease. Chest. 1988 Apr;93(4):688–692. doi: 10.1378/chest.93.4.688. [DOI] [PubMed] [Google Scholar]
  32. Stewart K. J. Resistive training effects on strength and cardiovascular endurance in cardiac and coronary prone patients. Med Sci Sports Exerc. 1989 Dec;21(6):678–682. doi: 10.1249/00005768-198912000-00010. [DOI] [PubMed] [Google Scholar]
  33. Vyas M. N., Banister E. W., Morton J. W., Grzybowski S. Response to exercise in patients with chronic airway obstruction. I. Effects of exercise training. Am Rev Respir Dis. 1971 Mar;103(3):390–400. doi: 10.1164/arrd.1971.103.3.390. [DOI] [PubMed] [Google Scholar]

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