Abstract
A patient developed fever, bronchoconstriction, hypoxaemia, pulmonary infiltrates, and serum and bronchoalveolar lavage fluid eosinophilia on two occasions after inhaling crack cocaine. Transbronchial biopsy specimens showed normal lung parenchyma but a dense eosinophilic infiltrate within the bronchial wall. Both episodes resolved promptly after treatment with corticosteroids. Eosinophilic lung disease may be a steroid responsive complication of crack cocaine abuse.
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- Allen J. N., Pacht E. R., Gadek J. E., Davis W. B. Acute eosinophilic pneumonia as a reversible cause of noninfectious respiratory failure. N Engl J Med. 1989 Aug 31;321(9):569–574. doi: 10.1056/NEJM198908313210903. [DOI] [PubMed] [Google Scholar]
- Badesch D. B., King T. E., Jr, Schwarz M. I. Acute eosinophilic pneumonia: a hypersensitivity phenomenon? Am Rev Respir Dis. 1989 Jan;139(1):249–252. doi: 10.1164/ajrccm/139.1.249. [DOI] [PubMed] [Google Scholar]
- Ettinger N. A., Albin R. J. A review of the respiratory effects of smoking cocaine. Am J Med. 1989 Dec;87(6):664–668. doi: 10.1016/s0002-9343(89)80401-2. [DOI] [PubMed] [Google Scholar]
- Gibson P. G., Dolovich J., Denburg J., Ramsdale E. H., Hargreave F. E. Chronic cough: eosinophilic bronchitis without asthma. Lancet. 1989 Jun 17;1(8651):1346–1348. doi: 10.1016/s0140-6736(89)92801-8. [DOI] [PubMed] [Google Scholar]
- Kissner D. G., Lawrence W. D., Selis J. E., Flint A. Crack lung: pulmonary disease caused by cocaine abuse. Am Rev Respir Dis. 1987 Nov;136(5):1250–1252. doi: 10.1164/ajrccm/136.5.1250. [DOI] [PubMed] [Google Scholar]
- Rebhun J. Association of asthma and freebase smoking. Ann Allergy. 1988 Apr;60(4):339–342. [PubMed] [Google Scholar]
- Taylor R. F., Bernard G. R. Airway complications from free-basing cocaine. Chest. 1989 Feb;95(2):476–477. doi: 10.1378/chest.95.2.476. [DOI] [PubMed] [Google Scholar]