BMET-02: EVALUATION OF DIFFERENT THERAPEUTIC MODALITIES FOR PRIMARY TREATMENT AND SALVAGE THERAPY AND THEIR RELATIVE COST IN PATIENTS WITH BRAIN METASTASES: A SINGLE INSTITUTION REPORT

BACKGROUND: Indications for whole brain radiotherapy (WBRT), stereotaxic radiosurgery (SRS) and craniotomy are not sufficiently well defined in a context of optimal care that takes into account cost effectiveness of therapy. Previous reports have shown contradictory results with regards to optimal care. Some favor loco-regional control while others preservation of neuro-cognitive function. We decided to review our own experience and trends in treatment with analysis focused not only on survival but as well treatment costs and use of salvage therapy. METHODS: Between January 2010 and 2015, we have treated 387 consecutive patients treated for brain metastasis. Chart review will collect the type of initial treatment as well as the type and the number of salvage treatment. The patients will be identified according to anatomic primary site and histology, age and gender, the date of initial diagnosis, performance status, number of brain metastasis and presence of other systemic metastasis. Local control and survival will be analyzed using the Kaplan Meier method, while age, gender, primary site location and initial method of treatment will be studied with COX univariate and multivariate analysis. Treatment cost for every patient will also be evaluated. RESULTS: Data analysis will be done between June and July 2015 and the results will be presented at the San Antonio SNO meeting.