Skip to main content
. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Bone. 2015 Sep 5;81:533–543. doi: 10.1016/j.bone.2015.09.003

Table 4.

Relative changes in gene expression 7 days after fracture in the OSX-Cre line

Gene of Interest Fold Change from Uninjured Limb (2^(dCTLeft- dCTRight))
BMP2 OSX-Cre Control BMP2 OSX-Cre cKO
n = 8 n= 7
Acan 1094 ± 968^ 1293 ± 1928^
Bmp2 1.3 ± 0.6 1.5 ± 0.3^“*
Bmp3 0.25 ± 0.09^ 0.30 ±0.11^
Bmp4 0.33 ± 0.14^ 0.37 ±0.12^
Bmp7 0.33 ± 0.19^ 0.30 ±0.08^
Bsp 10.1 ±7.7^ 7.3± 2.5^*
Chrd 3.5 ±1.9^ 5.3 ± 3.9^
Col1 7.0 ± 7.5^ 11.5 ± 7.8^
Col2 259 ± 357^ 169 ± 119^
Grem1 0.43 ±0.22^ 0.75 ±0.46
Nog 5.6 ±4.6^ 7.6 ± 6.7^
Osx 2.3 ± 1.4^ 2.4 ± 1.0^
Sox9 79.1 ± 68.2^ 95.9 ±53.6^
Vegf 1.4 ± 0.6 1.3 ± 0.8
^

p<0.05 Uninjured (Left) vs Fractured (Right), ANOVA with Paired Post-hoc Analysis

“

p<0.05 Uninjured Control vs Uninjured cKO, ANOVA with Unpaired Post-hoc Analysis

*

p<0.05 Fractured Control vs Fractured cKO, ANOVA with Unpaired Post-hoc Analysis