Table 2.

Association between severity of abdominal aortic calcification (AAC) and the risk of vertebral fracture in elderly women from the SOF study

	Adjusted for age	Adjusted for age, BMI, regular walking, smoking habits, HRT prevalent vertebral fracture, systolic blood pressure	Adjusted for age, BMI, regular walking, smoking habits, HRT, prevalent vertebral fracture, systolic blood pressure and total hip BMD	Adjusted for age, BMI, regular walking, smoking habits, HRT, prevalent vertebral fracture, systolic blood pressure, hip BMD and prior falls in past year	Adjusted for age, BMI, regular walking, smoking habits, HRT, prevalent vertebral fracture, systolic blood pressure, hip BMD prior falls in past year, and diabetes mellitus
	OR (95%CI)	OR (95%CI)	OR (95%CI)	OR (95%CI)	OR (95%CI)
4-year follow-up	n/N = 94/780	n/N = 92/768	n/N = 80/725	n/N = 79/722	n/N = 79/641
AAC score^#	1.06 (1.01 – 1.11)^a	1.05 (0.99 – 1.11)	1.07 (1.01 – 1.14)^a	1.07 (1.01 – 1.14)^a	1.07 (1.01 – 1.14)^a
AAC score = 0	1.00	1.00	1.00	1.00	1.00
AAC score = 1–4	1.65 (0.95 – 2.87)	1.41 (0.78 – 2.56)	1.49 (0.77 – 2.87)	1.39 (0.71 – 2.69)	1.38 (0.71 – 2.69)
AAC score = 5+	1.95 (1.13 – 3.35)^a	1.94 (1.09 – 3.44)^a	2.31 (1.24 – 4.30)^b	2.23 (1.19 – 4.17)^a	2.23 (1.19 – 4.17)^a
p for trend	<0.05	0.02	<0.01	0.01	0.01

15-year follow-up	n/N = 105/319	n/N = 104/310	n/N = 98/295	n/N = 98/294	n/N = 98/196
AAC score^#	0.98 (0.91 – 1.06)	0.98 (0.90– 1.06)	0.98 (0.90– 1.06)	0.98 (0.90– 1.06)	0.98 (0.90– 1.06)
AAC score = 0	1.00	1.00	1.00	1.00	1.00
AAC score =1–4	1.07 (0.60 – 1.89)	1.13 (0.60 – 2.13)	1.10 (0.57 – 2.12)	1.12 (0.58 – 2.17)	1.10 (0.57 – 2.14)
AAC score = 5+	0.91 (0.46 – 1.77)	0.93 (0.45 – 1.90)	0.93 (0.44 – 1.94)	0.94 (0.45 – 1.97)	0.93 (0.45 – 1.96)
p for trend	0.86	0.93	0.91	0.95	0.93

per 1 unit increase;

p<0.05,

p<0.01;

n - number of women with fractures in the analysis, N – total number of women in the analysis BMI – body mass index, BMD – bone mineral density, HRT – hormone replacement therapy