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. 2015 Nov 13;290(46):27532. doi: 10.1074/jbc.A110.210526

Neutralizing interleukin 1β (IL-1β) induces β-cell survival by maintaining PDX1 protein nuclear localization.

Amin Ardestani, Nadine S Sauter, Federico Paroni, Gitanjali Dharmadhikari, Jae-Hyoung Cho, Roberto Lupi, Piero Marchetti, José Oberholzer, Julie Kerr Conte, Kathrin Maedler
PMCID: PMC4646005  PMID: 26567296

VOLUME 286 (2011) PAGES 17144–17155

This article has been retracted by the publisher. Fig. 1E contained images that had been reused from the following references (Glas, R., Sauter, N. S., Schulthess, F. T., Shu, L., Oberholzer, J., and Maedler, K. (2009) Purinergic P2X7 receptors regulate secretion of interleukin-1 receptor antagonist and β cell function and survival. Diabetologia 52, 1579–1588 and Maedler, K., Schumann, D. M., Sauter, N., Ellingsgaard, H., Bosco, D., Baertschiger, R., Iwakura, Y., Oberholzer, J., Wollheim, C. B., Gauthier, B. R., and Donath, M. Y. (2006) Low concentration of interleukin-1β induces FLICE-inhibitory protein-mediated β-cell proliferation in human pancreatic islets. Diabetes 55, 2713–2722), and these reused images represented different experimental conditions.


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