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Scientific Reports logoLink to Scientific Reports
. 2015 Jul 20;5:9629. doi: 10.1038/srep09629

Corrigendum: Estimation of the hydrogen concentration in rat tissue using an airtight tube following the administration of hydrogen via various routes

Chi Liu, Ryosuke Kurokawa, Masayuki Fujino, Shinichi Hirano, Bunpei Sato, Xiao-Kang Li
PMCID: PMC4648425  PMID: 26190095

Scientific Reports 4: Article number: 5485 10.1038/srep05485; published online: June302014; updated on: July202015

This Article contains an error in describing the unit of hydrogen concentration in Figures 2-5: ‘ppb/g’ should read ‘ppm/g’ in the Y-axes. The correct Figures 2-5 appear below as Figures 1, 2, 3, 4 respectively.

Figure 1.

Figure 1

Figure 2.

Figure 2

Figure 3.

Figure 3

Figure 4.

Figure 4

In the Results section:

“Furthermore, a Cmax analysis showed that the oral administration of HSRW resulted in a high hydrogen concentration (more than 300 ppb/g) in the tissues of the spleen, small intestine and pancreas (Fig. 4A). Meanwhile, the intraperitoneal administration of HSRS resulted in a high hydrogen concentration in the spleen and pancreas (more than 300 ppb/g) (Fig. 4B). However, the hydrogen concentrations were not high (more than 35 ppb/g) in any of the tissues after intravenous treatment (Fig. 4C). Interestingly, the inhalation of hydrogen gas resulted in the highest hydrogen concentration in the muscle (more than 140 ppb/g; Fig. 4D).”

should read:

“Furthermore, a Cmax analysis showed that the oral administration of HSRW resulted in a high hydrogen concentration (more than 300 ppm/g) in the tissues of the spleen, small intestine and pancreas (Fig. 4A). Meanwhile, the intraperitoneal administration of HSRS resulted in a high hydrogen concentration in the spleen and pancreas (more than 300 ppm/g) (Fig. 4B). However, the hydrogen concentrations were not high (more than 35 ppm/g) in any of the tissues after intravenous treatment (Fig. 4C). Interestingly, the inhalation of hydrogen gas resulted in the highest hydrogen concentration in the muscle (more than 140 ppm/g; Fig. 4D).”

In the Methods section under ‘Tissue dissociation and the determination of the hydrogen concentrations in the arterial blood and tissues’:

“The hydrogen concentration in each blood or tissue sample was defined as follows: Hydrogen concentration (ppb/g; V/V) = A/B × C; where A is the measurement value obtained using the Sensor Gas Chromatograph, B is the blood or tissue weight (g) and C is the volume of the gentleMACS tube (24 ml).”

should read:

“The hydrogen concentration in each blood or tissue sample was defined as follows: Hydrogen concentration (ppm/g; V/V) = A/B × C; where A is the measurement value obtained using the Sensor Gas Chromatograph, B is the blood or tissue weight (g) and C is the volume of the gentleMACS tube (24 ml).”


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