Table 1. Association between ASC/TMS1 methylation and clinicopathological features of patients with RCC.
| Clinicopathological features | Number (n = 202) | ASC/TMS1 methylation status | P Value | |
|---|---|---|---|---|
| Methylated | Umethylated | |||
| Overall | 202 | 83(41.1) | 119(58.9) | |
| Gender: | ||||
| M | 138 | 59(42.8) | 79(57.2) | 0.540 |
| F | 64 | 24(37.5) | 40(62.5) | (Fisher's exact test) |
| Age: | ||||
| < 60(median) | 106 | 44(41.5) | 62(58.5) | 1.000 |
| ≥ 60 | 96 | 39(40.6) | 57(59.4) | (Fisher's exact test) |
| Side: | ||||
| Rt | 109 | 45(41.3) | 64(58.7) | 1.000 |
| Lt | 93 | 38(40.9) | 55(59.1) | (Fisher's exact test) |
| TNM classification: | ||||
| pT1a | 77 | 26(33.8) | 51(66.2) | 0.428 |
| pT1b | 68 | 31(45.6) | 37(54.4) | (chi-square test) |
| pT2 | 18 | 8(44.4) | 10(55.6) | |
| pT3 | 39 | 18(46.2) | 21(53.8) | |
| Nuclear grade: | ||||
| G1 | 49 | 14(28.6) | 35(71.4) | 0.005* |
| G2 | 128 | 51(39.8) | 77(60.2) | (chi-square test) |
| G3 | 25 | 17(68.0) | 8(32.0) | |
| Histological type: | ||||
| Clear cell Rcc | 185 | 79(42.7) | 106(57.3) | 0.305 |
| papillary Rcc | 9 | 2(22.2) | 7(77.8) | (chi-square test) |
| chromophobe Rcc | 8 | 2(25.0) | 6(75.0) | |