Table 2. Clinicopathological factors and RAD54B and RAD51 expression values in the training set (n = 123).
| Category | No (%) | RAD54B value | P value | RAD51 value | P value | |
|---|---|---|---|---|---|---|
| Sex | Male | 65 (52.8) | 2.46 (1.52-3.60) | 0.11 | 1.02 (0.71-1.50) | 0.65 |
| Female | 58 (47.2) | 2.78 (2.16-4.16) | 1.23 (0.84-1.62) | |||
| Age | <65 | 56 (45.5) | 2.72 (1.97-4.19) | 0.91 | 1.14 (0.81-1.56) | 0.97 |
| ≥65 | 67 (54.5) | 2.50 (2.10-3.65) | 1.15 (0.77-1.57) | |||
| Tumor location | Colon | 96 (78.0) | 2.69 (2.05-4.22) | 0.28 | 1.19 (0.79-1.58) | 0.34 |
| Rectum | 27 (22.0) | 2.42 (1.97-3.40) | 1.02 (0.80-1.48) | |||
| Tumor size (mm) | <50 | 66 (53.7) | 2.48 (2.05-3.24) | 0.12 | 1.17 (0.80-1.53) | 0.93 |
| ≥50 | 57 (46.3) | 2.88 (1.98-1.73) | 1.05 (0.78-1.58) | |||
| Cell differentiation | WD | 57 (46.3) | 2.48 (1.98-3.33) | 0.42 | 1.20 (0.79-1.56) | 0.68 |
| MD | 62 (50.4) | 2.62 (2.08-4.33) | 1.11 (0.78-1.57) | |||
| PD | 4 (3.3) | 4.47 (1.97-5.40) | 1.50 (0.82-2.74) | |||
| Lymphatic invasion | Positive | 47 (38.2) | 2.66 (1.57-4.57) | 0.92 | 1.35 (0.97-1.79) | 0.027 |
| Negative | 76 (61.8) | 2.56 (2.14-3.69) | 1.01 (0.79-1.48) | |||
| Venous invasion | Positive | 27 (22.0) | 2.58 (2.00-4.12) | 0.94 | 1.13 (0.80-1.57) | 0.97 |
| Negative | 96 (78.0) | 2.56 (2.05-3.41) | 1.18 (0.79-1.53) | |||
| Preoperative CEA | <5.0 | 61 (49.6) | 2.44 (1.87-4.11) | 0.67 | 1.17 (0.80-1.56 | 0.28 |
| ≥5.0 | 61 (49.6) | 2.72 (2.10-3.82) | 1.14 (0.79-1.56) | |||
| Preoperative CA19-9 | <37 | 99 (80.5) | 2.56 (1.98-3.78) | 0.59 | 1.10 (0.80-1.56) | 0.26 |
| ≥37 | 23 (18.7) | 2.97 (2.10-4.54) | 1.35 (0.69-1.93) | |||
| Tumor stage (UICC) | I | 13 (10.6) | 2.58 (2.13-3.04) | 0.20 | 1.09 (0.76-1.38) | 0.078 |
| II | 51(41.5) | 2.72 (223-4.45) | 1.18 (0.80-1.56) | |||
| III | 44 (35.8) | 2.42 (1.43-3.59) | 1.02 (0.73-1.53) | |||
| IV | 15 (12.2) | 2.98 (2.11-5.26) | 1.56 (1.13-2.67) | |||
| T stage | T1 | 5 (4.1) | 2.21 (1.05-5.31) | 0.16 | 0.68 (0.36-9.42) | 0.51 |
| T2 | 18 (14.6) | 2.76 (2.08-3.03) | 1.09 (0.87-1.40) | |||
| T3 | 60 (48.8) | 2.44 (1.62-3.94) | 1.13 (0.78-1.53) | |||
| T4 | 40 (32.5) | 2.87 (2.18-5.32) | 1.28 (0.81-1.79) | |||
| N stage | N0 | 67 (54.5) | 2.72 (2.21-3.87) | 0.23 | 1.15 (0.80-1.51) | 0.38 |
| N1 | 47 (38.2) | 2.46 (1.53-3.42) | 1.04 (0.78-2.28) | |||
| N2 | 9 (7.3) | 4.54 (1.77-4.00) | 1.39 (1.11-1.76) | |||
| Distant Recurrence in Stage I-III | Yes | 15 (12.2) | 3.87 (2.55-4.88) | 0.031 | 1.16 (0.81-1.79) | 0.69 |
| No | 93 (75.6) | 2.46 (1.92-3.24) | 1.07 (0.78-1.52) | |||
WD = well differentiated; MD = moderately differentiated; PD = poorly differentiated.