Table 3. Comparison of clinicopathological factors between RAD54B high and low groups.
| Category | Training set (n = 108) | P value | Validation set (n = 71) | P value | |||
|---|---|---|---|---|---|---|---|
| RAD54B Group | RAD54B Group | ||||||
| LOW (n = 79) | High (n = 29) | Low (n = 53) | High (n =18) | ||||
| No (%) | No (%) | No (%) | No (%) | ||||
| Sex | Male | 44 (55.7) | 13 (44.8) | 0.32 | 33 (62.3) | 10 (55.6) | 0.61 |
| Female | 35 (44.3) | 16 (55.2) | 20 (37.7) | 8(44.4) | |||
| Age | <65 | 32 (40.5) | 14 (48.3) | 0.47 | 22 (41.5) | 4 (22.2) | 0.14 |
| ≥65 | 47 (59.5) | 15 (51.7) | 31 (58.5) | 14 (77.8) | |||
| Tumor location | Colon | 58 (73.4) | 26 (89.7) | 0.072 | 37 (69.8) | 12 (66.7) | 0.80 |
| Rectum | 21 (26.6) | 3(10.3) | 16 (30.2) | 6(33.3) | |||
| Tumor size (mm) | <50 | 48 (60.8) | 14 (48.3) | 0.24 | 28 (52.8) | 8 (4.4.4) | 0.54 |
| ≥50 | 31 (39.2) | 15 (51.7) | 25 (47.2) | 10 (55.6) | |||
| Cell differentiation | WD | 41 (51.9) | 12 (41.4) | 0.33 | 26 (49.1) | 6 (33.3) | 0.25 |
| MD/PD | 38 (48.1) | 17 (58.6) | 27 (50.9) | 12 (66.7) | |||
| Lymphatic invasion | Positive | 24 (30.4) | 12 (41.4) | 0.28 | 19 (35.8) | 3 (16.7) | 0.13 |
| Negative | 55 (69.6) | 17 (58.6) | 34 (64.2) | 15 (83.3) | |||
| Venous invasion | Positive | 59 (74.7) | 5 (17.2) | 0.38 | 37 (69.8) | 12 (66.7) | 0.80 |
| Negative | 20 (25.3) | 24 (82.8) | 16 (30.2) | 6(33.3) | |||
| Preoperative CEA | <5.0 | 41 (51.9) | 16 (55.2) | 0.76 | 29 (54.7) | 7(38.9) | 0.25 |
| ≥5.0 | 38 (48.1) | 13 (44.8) | 24 (45.3) | II (61.1) | |||
| Preoperative CA19-9 | <37 | 69 (87.3) | 24 (82.8) | 0.88 | 43(81.1) | 15 (83.3) | 0.83 |
| ≥37 | 10 (12.3) | 5(17.2) | 10 (18.9) | 3(16.7) | |||
| Tumor stage (UICC) | I | 12 (15.2) | 1(3.4) | 0.17 | 7(13.2) | 3(16.7) | 0.88 |
| II | 34 (43.0) | 17 (58.6) | 19 (35.8) | 7 (38.9) | |||
| III | 33 (41.8) | 11 (37.9) | 27 (50.9) | 8(44.4) | |||
| T stage | T1-2 | 21 (26.6) | 2(6.9) | 0.027 | 9(17.0) | 4 (22.2) | 0.62 |
| T3-4 | 58 (73.4) | 27 (93.1) | 44 (83.0) | 14 (77.8) | |||
| N stage | N0 | 46 (58.2) | 18 (62.1) | 0.72 | 26 (49.1) | 11 (61.1) | 0.38 |
| N1-2 | 33 (41.8) | 11(37.9) | 27 (50.9) | 7(38.9) | |||
| Adjuvant chemotherapy | Yes | 24 30.4) | 9 31.0) | 0.95 | 23 (43.4) | 6 (33.3) | 0.45 |
| No | 55 (69.6) | 20 (69.0) | 30 (56.6) | 12 (66.7) | |||
| Distant Recurrence | Yes | 6 (7.6) | 9 (31.0) | 0.0018 | 7 (13.2) | 7 (38.9) | 0.024 |
| No | 73 (92.4) | 20 (69.0) | 46 (86.8) | 11 (61.1) | |||
WD = well differentiated; MD = moderately differentiated; PD = poorly differentiated.