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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Neuroepidemiology. 2015 Oct 27;45(4):264–272. doi: 10.1159/000439592

Table 2.

Associations Between Risk Factors and Cogstate Scores*

DET (n=1,620) IDN (n=1,591) OCL (n=1,546) ONB (n=1,576)
β p β p β p β p
Age (years) 0.002 (0.002, 0.003) <0.001 0.002 (0.001, 0.002) <0.001 −0.004 (−0.005, −0.003) <0.001 0.004 (0.003, 0.004) <0.001
Body mass index
   <22 kg/m2 0.007 (−0.011, 0.025) 0.46 −0.002 (−0.014, 0.011) 0.76 −0.008 (−0.030, 0.013) 0.44 0.010 (−0.007, 0.027) 0.23
   22–24.9 kg/m2 (ref.) - - - - - - - -
   25–29.9 kg/m2 −0.001 (−0.012, 0.010) 0.87 −0.003 (−0.010, 0.005) 0.49 −0.016 (−0.029, −0.002) 0.02 −0.012 (−0.022, −0.002) 0.02
   30+ kg/m2 −0.007 (−0.022, 0.009) 0.40 −0.008 (−0.019, 0.003) 0.14 −0.021 (−0.040, −0.002) 0.03 −0.023 (−0.037, −0.008) 0.002
Physical activity, MET-hr/wk
   First quartile (ref.) - - - - - - - -
   Second quartile −0.001 (−0.014, 0.012) 0.88 −0.004 (−0.013, 0.005) 0.38 0.014 (−0.003, 0.030) 0.10 0.002 (−0.010, 0.015) 0.74
   Third quartile 0.001 (−0.013, 0.015) 0.88 −0.002 (−0.011, 0.008) 0.76 0.005 (−0.011, 0.022) 0.53 0.003 (−0.010, 0.016) 0.61
   Fourth quartile −0.007 (−0.021, 0.007) 0.32 −0.005 (−0.015, 0.004) 0.28 0.007 (−0.010, 0.023) 0.44 0.001 (−0.012, 0.014) 0.92
   p-trend 0.29 0.42 0.89 0.99
Alcohol, servings/day
   None (ref.) - - - - - - - -
   1–2 −0.012 (−0.022, −0.002) 0.02 −0.003 (−0.010, 0.004) 0.47 0.000 (−0.012, 0.013) 0.95 −0.008 (−0.017, 0.002) 0.10
   >2 0.005 (−0.009, 0.019) 0.51 0.001 (−0.009, 0.011) 0.87 0.000 (−0.016, 0.017) 0.96 0.001 (−0.012, 0.014) 0.88
Nut Intake, servings
   <1/month (ref.) - - - - - - - -
   1–3/month 0.001 (−0.018, 0.021) 0.89 0.002 (−0.012, 0.016) 0.81 0.017 (−0.007, 0.041) 0.15 −0.004 (−0.023, 0.014) 0.65
   1–2/week −0.012 (−0.028, 0.004) 0.15 −0.003 (−0.014, 0.009) 0.66 0.022 (0.003, 0.042) 0.03 −0.010 (−0.026, 0.005) 0.18
   >2/week −0.013 (−0.029, 0.003) 0.10 −0.004 (−0.016, 0.007) 0.46 0.018 (−0.001, 0.038) 0.06 −0.014 (−0.029, 0.001) 0.07
   p-trend 0.12 0.33 0.59 0.10
Fish Intake, servings
   <1/month (ref.) - - - - - - - -
   1–3/month 0.001 (−0.021, 0.023) 0.91 −0.001 (−0.016, 0.015) 0.95 −0.004 (−0.030, 0.022) 0.77 0.018 (−0.002, 0.038) 0.08
   1–2/week −0.006 (−0.025, 0.013) 0.53 −0.007 (−0.020, 0.006) 0.28 −0.005 (−0.028, 0.017) 0.64 0.004 (−0.014, 0.021) 0.69
   >2/week −0.007 (−0.026, 0.013) 0.49 −0.002 (−0.015, 0.012) 0.81 0.000 (−0.023, 0.024) 0.98 0.006 (−0.012, 0.024) 0.49
   p-trend 0.38 0.74 0.59 0.84
Diabetes 0.013 (−0.003, 0.030) 0.11 0.009 (−0.003, 0.020) 0.13 0.016 (−0.004, 0.036) 0.12 0.000 (−0.015, 0.015) 0.99
Hypertension 0.004 (−0.006, 0.013) 0.45 0.007 (0.000, 0.013) 0.049 −0.009 (−0.020, 0.003) 0.13 0.006 (−0.002, 0.015) 0.15
Myocardial infarction −0.001 (−0.019, 0.017) 0.92 −0.009 (−0.022, 0.003) 0.14 0.000 (−0.022, 0.022) 0.99 −0.005 (−0.021, 0.012) 0.60
*

Lower scores indicate better performance for DET, IDN, and ONB. Higher scores indicate better performance for OCL. All variables were placed into the same model.