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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: Neuropharmacology. 2015 Oct 22;101:351–357. doi: 10.1016/j.neuropharm.2015.10.013

Figure 2.

Figure 2

Direct infusion of mefloquine into nucleus accumbens promotes social avoidance behavior following subthreshold social defeat stress. (a) Schematic depicting bilateral cannula placements for all animals included in analysis (n=6–7 mice/group). Images are modified from Paxinos and Franklin, 2001. (b) Experimental timeline. (c) Mefloquine administration decreased interaction duration in the social interaction test one day following stress and drug infusion (*p<0.01, two-way repeated measures ANOVA, n=6–7 mice/group). (d) Animals that received mefloquine had a lower social interaction ratio (*p<0.01, Student’s t-test). (e) Representative heat maps from the target present trial. Data are represented as group means. Error bars represent SEM.