Table 3.

Consistency of Pain Relief Across Multiple Migraines

	30 minutes	1 hour	2 hours
Pain relief for the first 2 migraines in each treatment period, percentage of subjects who treated ≥2 attacks in both periods
AVP-825 (n = 165)	37.6	52.1	64.2
Oral sumatriptan (n = 165)	18.8	45.5	62.4
P value	<.001	.20	.80
Pain relief for ≥2 of the first 3 migraines in each treatment period, percentage of subjects who treated ≥3 attacks in both periods
AVP-825 (n = 140)	51.4	71.4	83.6
Oral sumatriptan (n = 140)	33.6	64.3	81.4
P value	<.001	.17	.68
Pain relief for 3 of the first 3 migraines in each treatment period, percentage of subjects who treated ≥3 attacks in both periods
AVP-825 (n = 140)	27.1	41.4	57.9
Oral sumatriptan (n = 140)	12.1	40.7	57.1
P value	<.001	1.0	1.0

Pain relief is defined as reduction of Headache Severity score from moderate or severe to none or mild.

P values are based on McNemar’s test.