Table 4.
Summary of Worst Adverse Event per Patient (definitely, probably, or possibly related to treatment) comparing RTOG 9708 with RTOG 0921
| Grade | AEs ≤90 days from the start of all RX1 | AEs >90 days from the start of all RX2 | AEs occurring during concurrent RX3 | AEs occurring during adjuvant chemo4 | |||
|---|---|---|---|---|---|---|---|
| RTOG 0921 | RTOG 0921 | RTOG 9708 | RTOG 0921 | RTOG 9708 | RTOG 0921 | RTOG 9708 | |
| 1 | 0 ( 0%) | 3 (10%) | 9 (20%) | 1 ( 3%) | 12 (27%) | 0 ( 0%) | 3 ( 7%) |
| 2 | 10 (33%) | 10 (33%) | 17 (39%) | 9 (30%) | 19 (43%) | 6 (20%) | 3 ( 7%) |
| 3 | 11 (37%) | 9 (30%) | 7 (16%) | 7 (23%) | 12 (27%) | 12 (40%) | 9 (21%) |
| 4 | 5 (17%) | 6 (20%) | 1 ( 2%) | 2 ( 7%) | 1 ( 2%) | 6 (20%) | 26 (62%) |
| 5 | 0 ( 0%) | 0 ( 0%) | 0 ( 0%) | 0 ( 0%) | 0 ( 0%) | 0 ( 0%) | 0 ( 0%) |
Key: RX=treatment
1
AE date ≤ (start of all treatment +90 days)
2
AE date > (start of all treatment +90 days)
3
Concurrent treatment start date ≤ AE date ≤ concurrent treatment end date
4
Adjuvant treatment start date ≤ AE date ≤ adjuvant treatment end date