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Primary composite outcome by rs10911021 genotype and lifestyle intervention. The incidence of the primary outcome (death from cardiovascular causes, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for angina) over a 9.6-year median follow-up by rs10911021 genotype and randomized study intervention arm. Solid lines denote participants randomized to ILI, and dashed lines indicate randomization to DSE.
